The Mass Spectrometry facility is located at 2323 FFSC. A number of walk-up instruments are available for Duke researchers once they have completed training, and additional instruments are available for assisted operation with Facility staff. The available instruments are:
Agilent LC/MSD Trap
- Capabilities include ESI-MS using direct infusion or capillary HPLC
- Open access after training, or assisted operation available
Shimadzu QP2010 GCMS
- Capabilities include GC with EI (low resolution) and auto-sampler/auto-injector
- Open access after training, or assisted operation available
Agilent 6224 LC/MS-TOF (High-Resolution)
- Capabilities include ESI-MS using either flow injection or conventional HPLC
- Agilent 1200 HPLC with a variety of HPLC columns and UV detection
- Mass accuracy within +/- 3 ppm for mass confirmation and publication
- Operated by staff, or assisted operation available (experienced users)
- Funding Reference for Publications: NSF Award No. CHE-0923097
Agilent 6460 Triple Quadrupole LC-MS
- Capabilities include LC-MS/MS (conventional flow, or nano-flow/nano-spray with Chip Cube interface)
- Agilent 1260 with a variety of HPLC columns and UV detection
- Operated by staff, or assisted operation available (experienced users)
- Funding Reference for Publications: NSF Award No. CHE-1531119
Bruker Autoflex Speed LRF MALDI-TOF System
- Capabilities include both linear and reflectron detection
- Open access after training, or assisted operation available
- Funding Reference for Publications: North Carolina Biotechnology Center Grant #2017-IDG-1018
