Derbyshire Lab Takes Aim at Human Cell Machinery


A team effort by the Derbyshire lab has led to the identification of human genes and pathways that facilitate the infection of liver cells by Plasmodium parasites, the causative agents of malaria. Their results suggest that this parasite co-opts the vesicular trafficking of its host cell to support its dramatic growth during the liver stage of infection. This work provides insights into the poorly understood interactions between Plasmodium parasites and the host liver cells they invade. Learn more about their findings in a recent Cell Chemical Biology, available here and highlighted in Duke Today.