Lizzie Hunsaker of the Franz lab has discovered that modulating copper levels in the growth environment of Candida albicans reduces tolerance of this pathogen to widely prescribed azole antifungal drugs.

The Malcolmson lab has demonstrated that internal dienes may undergo regio- and enantioselective additions of enolate pronuclephiles.

Rene Raphemot, Amber Eubanks, and other members of the Derbyshire lab, in collaboration with the Haystead lab in the Pharmacology department, have discovered the first reported inhibitors of an atypical Plasmodium kinase - PK9.

An international collaboration with the Beratan lab reports in Proceedings of the National Academy of Sciences that voltages may induce coherent long-range electron transport through biomolecules and other molecular structures. The authors describe a novel transport mechanism that suppor

The Roizen laboratory is developing a strategy to employ the intrinsic geometric constraints of a molecule to alter of the site of C-H functionalization reactions.

The Malcolmson lab has recently shown that gem-difluoroazadienes can serve as a novel building block for the synthesis of chiral alpha-trifluoromethyl amines via the vicinal fluoro-functionalization of its alkene.

The Hargrove Lab has created a general, high throughput technique for screening small molecule probes against different RNA targets using a fluorescence indicator displacement (FID) assay. Learn more about their fast and convenient method to simultaneously evaluate small molecule libraries agains

Graduate student Meredith Barbee and co-workers in the Craig lab and at Texas State have used a mixture of classical physical organic methodology and contemporary single molecule spectroscopy to tease out mechanistic details of a reaction occurring under large mechanical forces. Their

Agostino Migliore, Darius Teo and additional members of the Beratan Lab, with collaborators at USC, take an important step towards understanding intracellular redox signaling at the core of DNA repair and replication processes.

The static correlation error inherent in commonly used density functional approximations (DFAs) has seriously hindered the application of density functional theory (DFT) to strongly correlated systems.