Research + Discoveries

Wang, Malcolmson and Warren Labs Promoting Hyperpolarization of 15N2-Diazirines for Novel NMR/MR Imaging Strategies

The Wang, Malcolmson and Warren labs have teamed up to use diazirines as molecular imaging tags for biomedical applications.  Diazirines are an attractive class of potential molecular tags for magnetic resonance imaging with their biocompatibility and ease of incorporation into a large variety of molecules.  The team has recently demonstrated with a 15N2-diazirine-containing choline derivative that 15N2-diazirines are capable of supporting long-lasting polarization, representing promising molecular tags in NMR/MR imaging.   Read more about their work (and view their cover!) in the September 25 issue of Angewandte Chemie here