The Wang, Malcolmson and Warren labs have teamed up to use diazirines as molecular imaging tags for biomedical applications. Diazirines are an attractive class of potential molecular tags for magnetic resonance imaging with their biocompatibility and ease of incorporation into a large variety of molecules.Read More
Equilibrating glass-forming liquids is notoriously hard; Duke chemists and their collaborators in France have developed a way to circumvent this obstacle, enabling studies of extremely sluggish liquids. The results were just published in Proceedings the National Academy of Sciences and Physical Review Letters.Read More
A recent publication in Nature Communications on selective carbon dioxide hydrogenation using plasmonic rhodium catalysts by the Liu lab and collaborators has been selected as one of eight featured articles in the Nature Research “Understanding Catalysis” collection.Read More
The Hargrove Lab compared bioactive ligands that target RNA to current FDA-approved drugs, nearly all of which target proteins. With the help of the Beratan Lab, they identified key differences in physical, structural, and spatial properties that distinguish RNA-targeted bioactive ligands. These unique insights are expected to facilitate the selection and synthesis of RNA-targeted libraries with the goal of efficiently identifying selective small molecule ligands for therapeutically relevant RNAs.Read More
The Therien Lab, teamed with chemists at UC San Francisco, have created a synthetic protein that tightly binds a non-biological catalyst, a type of molecule called porphyrin that is capable of stealing electrons from other molecules when it absorbs light. Read more about how the “protein gator” chomps porphyrin cofactors in the Nature Chemistry article available here.