Research + Discoveries

  • Toward a Molecular "Double-slit" Experiment

    A Physics Today article describes new experiments that are testing predictions of Professor David Beratan's group on how infra-red radiation may be used to gate charge flow through molecules.  The recent experiment are testing Beratan's ideas of how vibrational excitation may be used to modulate electronic coupling "pathways" and their quantum mechanical interferences in molecules.  The writeup appears here 

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  • New Approach Creates Property-Biased Molecular Libraries in silico

    A paper by Chetan Rupakheti and Aaron Virship, in collaboration with Professors Yang and Beratan, reports a new approach to develop property-biased molecular libraries that capture the diversity of vast "molecular space."  The paper was selected as an Editors' Choice in the /Journal of Chemical Information and Modeling/ and is available as a "just accepted" manuscript at:

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  • Gold Carbene Complex Lacking Heteroatom Stabilization

    The Widenhoefer group has  recently reported the synthesis and structure of the first gold carbene complex lacking heteroatom stabilization.  Unstabilzied gold carbene complexes have been widely invoked as reactive intermediates in gold- catalyzed transformations but have heretofore escaped direct detection and characterization.  This work, co-authored with graduate student Robert Harris, recently appeared in Angewandte Chemie.

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  • Migliore and Collaborators re-ignite interest in DNA-based wires

    Dr Agostino Migliore and collaborators are taking a major step forward in understanding the basic rules of charge transport through long polymer  wires and in their implementation in more complex electrical circuits. Their work recently appeared in Nature Nanotechnology and is a result of an international collaboration led by the experimental group of Prof. Danny Porath (from The Hebrew University of Jerusalem) and involving experimentalists and theorists from Israel, USA, and Europe.

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  • Professor Derbyshire and Colleagues Find New Ways to Fight Malaria

    Professor Derbyshire is the lead author on a new study that identifies several kinase inhibitors that show promise as anti-malarial drugs.  The work, which was recently published online in ChemBioChem, was also highlighted in the August 25, 2014 article in Duke Today and in the October 2, 2014 article in Duke Today.

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