The Fitzgerald Group recently described the development and application of two new experimental protocols that significantly expand the scope of their SPROX methodology for the large-scale and high-throughput analysis of protein-ligand binding interactions on the proteomic scale. The work is reported in two recently published papers, one in Analytical Chemistry that is co-authored by graduate student researchers Yingrong Xu and Erin Strickland and the other in Molecular and Cellular Proteomics that is co-authored by graduate student researchers Duc Tran and Jagat Adhikari.
