Fitzgerald Group


Xu, Ying, et al. “Mass spectrometry- and lysine amidination-based protocol for thermodynamic analysis of protein folding and ligand binding interactions.Analytical Chemistry, vol. 83, no. 9, May 2011, pp. 3555–62. Epmc, doi:10.1021/ac200211t. Full Text

DeArmond, Patrick D., et al. “Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures.Journal of the American Society for Mass Spectrometry, vol. 22, no. 3, Mar. 2011, pp. 418–30. Epmc, doi:10.1007/s13361-010-0060-1. Full Text

Xu, Y., et al. “Xu, Y., Falk, I.N., Hallen, M.A., and Fitzgerald, M.C.Analytical Chemistry, no. 83, 2011, pp. 3555–62.

Dearmond, Patrick D., et al. “Discovery of novel cyclophilin A ligands using an H/D exchange- and mass spectrometry-based strategy.J Biomol Screen, vol. 15, no. 9, Oct. 2010, pp. 1051–62. Pubmed, doi:10.1177/1087057110382775. Full Text

Kim, Hyoungsu, et al. “Total synthesis, assignment of the absolute stereochemistry, and structure-activity relationship studies of subglutinols A and B.Chemistry, an Asian Journal, vol. 5, no. 8, Aug. 2010, pp. 1902–10. Epmc, doi:10.1002/asia.201000147. Full Text

West, Graham M., et al. “Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.Anal Chem, vol. 82, no. 13, July 2010, pp. 5573–81. Pubmed, doi:10.1021/ac100465a. Full Text Open Access Copy

West, Graham M., et al. “Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 20, May 2010, pp. 9078–82. Epmc, doi:10.1073/pnas.1000148107. Full Text

Xu, Ying, et al. “Thermodynamic analysis of a molecular chaperone binding to unfolded protein substrates.Biochemistry, vol. 49, no. 6, Feb. 2010, pp. 1346–53. Epmc, doi:10.1021/bi902010t. Full Text Open Access Copy

DeArmond, P. D., et al. “Discovery of Novel Cyclophilin A Ligands Using an H/D Exchange- and Mass Spectrometry-Based Strategy. Journal of Biomolecular Screening.Journal of Biomolecular Screening, vol. 15, no. 9, 2010, pp. 1051–62.

Hopper, Erin D., et al. “Hydrogen/deuterium exchange- and protease digestion-based screening assay for protein-ligand binding detection.Anal Chem, vol. 81, no. 16, Aug. 2009, pp. 6860–67. Pubmed, doi:10.1021/ac900854t. Full Text