Spring 2019

Course Number Title Instructor(s) Location Time Synopsis
CHEM 518 Wang, Qiu French Sci 2237 WF 08:30 AM-09:45 AM


CHEM 533 Widenhoefer, Ross
Bobay, Benjamin
French Sci 2237 TuTh 10:05 AM-11:20 AM


CHEM 535 Hong, Jiyong French Sci 2237 TuTh 08:30 AM-09:45 AM


CHEM 536 McCafferty, Dewey LSRC A156 MWF 10:20 AM-11:10 AM


CHEM 538 Malcolmson, Steven French Sci 2237 MW 11:45 AM-01:00 PM


CHEM 590 Welsher, Kevin
Roy, Christopher
LSRC B105 TuTh 08:30 AM-09:45 AM


CHEM 611 Franklin, Aaron Bryan Center GRIFFITH F TuTh 10:05 AM-11:20 AM


CHEM 630 Vo-Dinh, Tuan Hudson 125 TuTh 03:05 PM-04:20 PM


Non-Chemistry courses that apply to Chemistry doctoral degree

Biochemistry 658. Structural Biochemistry I. Principles of modern structural biology. Protein-nucleic acid recognition, enzymatic reactions, viruses, immunoglobulins, signal transduction, and structure-based drug design described in terms of the atomic properties of biological macromolecules. Discussion of methods of structure determination with particular emphasis on macromolecular X-ray crystallography NMR methods, homology modeling, and bioinformatics. Students use molecular graphics tutorials and Internet databases to view and analyze structures. Prerequisites: organic chemistry and introductory biochemistry. Instructors: Beese and staff. 2 units. C-L: Cell and Molecular Biology 658, Cell Biology 658, University Program in Genetics 658, Immunology 658, Structural Biology and Biophysics 658, Computational Biology and Bioinformatics 658

Biochemistry 659. Structural Biochemistry II. Continuation of Biochemistry 658. Structure/function analysis of proteins as enzymes, multiple ligand binding, protein folding and stability, allostery, protein-protein interactions. Prerequisites: Biochemistry 658, organic chemistry, physical chemistry, and introductory biochemistry. Instructors: Zhou and staff. 2 units. C-L: Cell Biology 659, Immunology 659, Computational Biology and Bioinformatics 659, Structural Biology and Biophysics 659, University Program in Genetics 659

Biochemistry 681. Physical Biochemistry. A structure-based introduction to the role of thermodynamic driving forces in biology. An overview of experimental sources of structural and dynamic data, and a review of the fundamental concepts of thermodynamics. Both concepts are combined to achieve a structural and quantitative mechanistic understanding of allosteric regulation, and of coupled ligand binding and conformational change. Statistical thermodynamics is used to develop ensemble models of protein and nucleic acid dynamics. This treatment leads into specific examples and general principles of how to interpret structural and dynamic information toward the purposes of other research. Instructor consent required. Instructor: Oas. 3 units. C-L: Structural Biology and Biophysics 681

Civil and Environmental Engineering 563. Chemical Fate of Organic Compounds. Equilibrium, kinetic, and analytical approaches applied to quantitative description of processes affecting the distribution and fate of anthropogenic and natural organic compounds in surface and groundwaters, including chemical transfers between air, water, soils/sediments, and biota; and thermochemical and photochemical transformations. The relationships between organic compound structure and environmental behavior will be emphasized. Sampling, detection, identification, and quantification of organic compounds in the environment. Prerequisites: university-level general chemistry and organic chemistry within last four years. Instructor: Stapleton

Electrical and Computer Engineering/Nanoscience 511. Foundations of Nanoscale Science and Technology. This course is the introductory course for the Graduate Certificate Program in Nanoscience (GPNANO) and is designed to introduce students to the interdisciplinary aspects of nanoscience by integrating important components of the broad research field together. This integrated approach will cross the traditional disciplines of biology, chemistry, electrical & computer engineering, computer science, and physics. Fundamental properties of materials at the nanoscale, synthesis of nanoparticles, characterization tools, and self-assembly. Prerequisites: Physics 152L and Chemistry 101DL or instructor approval. Instructor: Dwyer. 3 units. C-L: Nanosciences 511 

Mechanical Engineering 514. Theoretical and Applied Polymer Science (GE, BB).An intermediate course in soft condensed matter physics dealing with the structure and properties of polymers and biopolymers. Introduction to polymer syntheses based on chemical reaction kinetics, polymer characterization. Emphasizes (bio)polymers on surfaces and interfaces in aqueous environments, interactions of (bio)polymer surfaces, including wetting and adhension phenomena. Instructor: Zauscher. 3 units. C-L: Biomedical Engineering 529

Pharmacology and Cancer Biology 533. Essentials of Pharmacology and Toxicology. Drug absorption, distribution, excretion, and metabolism. Structure and activity relationships; drug and hormone receptors and target cell responses. Consent of instructor required. Prerequisite: introductory biology; Chemistry 201DL; Mathematics 21 and 122. Instructor: Slotkin and staff. 4 units. C-L: Neuroscience 533

Pharmacology and Cancer Biology 835. Innovations in Drug Development. Introduction to major issues in developing a drug to treat a disease in an interdisciplinary lecture-based and team-based learning environment. Translation of principles in biomedical sciences, biomedical engineering, and chemistry along with innovative approaches to develop a hypothetical drug for treating a disease of choice. Hypothetical development of model compounds, target analysis, and in vitro and in vivo models to test drug efficacy. Course requires one of the following (or equivalent): Pharm 533, Chem 518, or BME 577 Instructor: Bloom