Faculty Profiles

Warren S. Warren
James B. Duke Professor of Chemistry
2217 French Science Center, Durham, NC 27708
(919) 660-1604
(919) 287-2454



Ph.D., University of California at Berkeley 1980

M.S., University of California at Berkeley 1979

Research Areas:
Physical, Biomolecular Structure and Function

Bae, J, Zhou, Z, Theis, T, Warren, WS, and Wang, Q. "15N4-1,2,4,5-tetrazines as potential molecular tags: Integrating bioorthogonal chemistry with hyperpolarization and unearthing para-N2." Science Advances 4.3 (March 9, 2018): eaar2978-null. Full Text

Shchepin, RV, Jaigirdar, L, Theis, T, Warren, WS, Goodson, BM, and Chekmenev, EY. "Spin Relays Enable Efficient Long-Range Heteronuclear Signal Amplification By Reversible Exchange." The Journal of Physical Chemistry. C, Nanomaterials and Interfaces 121.51 (December 2017): 28425-28434. Full Text

Puza, CJ, Warren, WS, and Mosca, PJ. "Correction to: The changing landscape of dermatology practice: melanoma and pump-probe laser microscopy." Lasers in Medical Science 32.9 (December 2017): 2173-null. Full Text

Shen, K, Logan, AWJ, Colell, JFP, Bae, J, Ortiz, GX, Theis, T, Warren, WS, Malcolmson, SJ, and Wang, Q. "Diazirines as Potential Molecular Imaging Tags: Probing the Requirements for Efficient and Long-Lived SABRE-Induced Hyperpolarization." Angewandte Chemie (International Ed. in English) 56.40 (September 2017): 12112-12116. Full Text

Wilson, JW, Robles, FE, Deb, S, Warren, WS, and Fischer, MC. "Comparison of pump-probe and hyperspectral imaging in unstained histology sections of pigmented lesions." Biomedical Optics Express 8.8 (August 2017): 3882-3890. Full Text

Shchepin, RV, Goodson, BM, Theis, T, Warren, WS, and Chekmenev, EY. "Toward Hyperpolarized 19 F Molecular Imaging via Reversible Exchange with Parahydrogen." Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry 18.15 (August 2017): 1961-1965. Full Text

Zhou, Z, Yu, J, Colell, JFP, Laasner, R, Logan, A, Barskiy, DA, Shchepin, RV, Chekmenev, EY, Blum, V, Warren, WS, and Theis, T. "Long-Lived 13C2 Nuclear Spin States Hyperpolarized by Parahydrogen in Reversible Exchange at Microtesla Fields." The Journal of Physical Chemistry Letters 8.13 (July 2017): 3008-3014. Full Text

Colell, JFP, Emondts, M, Logan, AWJ, Shen, K, Bae, J, Shchepin, RV, Ortiz, GX, Spannring, P, Wang, Q, Malcolmson, SJ, Chekmenev, EY, Feiters, MC, Rutjes, FPJT, Blümich, B, Theis, T, and Warren, WS. "Direct Hyperpolarization of Nitrogen-15 in Aqueous Media with Parahydrogen in Reversible Exchange." Journal of the American Chemical Society 139.23 (June 2017): 7761-7767. Full Text

Barskiy, DA, Shchepin, RV, Tanner, CPN, Colell, JFP, Goodson, BM, Theis, T, Warren, WS, and Chekmenev, EY. "The Absence of Quadrupolar Nuclei Facilitates Efficient 13 C Hyperpolarization via Reversible Exchange with Parahydrogen." Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry 18.12 (June 2017): 1493-1498. Full Text

Robles, FE, Deb, S, Fischer, MC, Warren, WS, and Selim, MA. "Label-Free Imaging of Female Genital Tract Melanocytic Lesions With Pump-Probe Microscopy: A Promising Diagnostic Tool." Journal of Lower Genital Tract Disease 21.2 (April 2017): 137-144. Full Text


Warren, WS. The Physical Basis of Chemistry.: Elsevier, July 14, 2015.

Wilson, JW, Vajzovic, L, Robles, FE, Cummings, TJ, Mruthyunjaya, P, and Warren, WS. "Imaging pigment chemistry in melanocytic conjunctival lesions with pump-probe microscopy.": SPIE. March 26, 2013. Full Text

Warren, WS. "Understanding Melanoma Biochemistry/Metastatic Potential with Pump-probe Microscopy." Optical Molecular Probes, Imaging and Drug Delivery. 2017.: OSA, 2017. Full Text

Wilson, JW, Warren, WS, and Fischer, MC. "Real-time digital signal processing in multiphoton and time-resolved microscopy." SPIE BiOS.: SPIE, March 7, 2016. Full Text

Robles, FE, Selim, MA, and Warren, WS. "Diagnosis and staging of female genital tract melanocytic lesions using pump-probe microscopy (Conference Presentation)." Conference on Photonic Therapeutics and Diagnostics XII. February 13, 2016 - February 14, 2016. San Francisco, CA.: SPIE-INT SOC OPTICAL ENGINEERING, January 1, 2016. Full Text

Warren, WS. "Enhancing Tissue and Cultural Heritage Imaging with Ultrafast Nonlinear Optics." International Conference on Fibre Optics and Photonics. 2016.: OSA, 2016. Full Text

Warren, WS, Robles, F, Fischer, M, Wilson, J, Deb, S, Ju, K, and Degan, S. "Melanin-targeted nonlinear microscopy for label-free molecular diagnosis and staging." Clinical and Translational Biophotonics. 2016.: OSA, 2016. Full Text

Robles, FE, Fischer, MC, and Warren, WS. "Dispersion-based stimulated Raman scattering spectroscopy, holography, and optical coherence tomography (Conference Presentation)." Conference on Multiphoton Microscopy in the Biomedical Sciences XVI. February 14, 2016 - February 16, 2016. San Francisco, CA.: SPIE-INT SOC OPTICAL ENGINEERING, January 1, 2016. Full Text

Wilson, JW, Anderson, M, Park, JK, Fischer, MC, and Warren, WS. "Separating higher-order nonlinearities in transient absorption microscopy." SPIE Optical Engineering + Applications.: SPIE, August 26, 2015. Full Text

Villafana, TE, Brown, W, Warren, WS, and Fischer, M. "Ultrafast pump-probe dynamics of iron oxide based earth pigments for applications to ancient pottery manufacture." SPIE Optical Metrology.: SPIE, June 30, 2015. Full Text

Wilson, JW, Degan, S, Gainey, CS, Deb, S, Dall, CP, Tameze-Rivas, Y, Zhang, J, and Warren, WS. "In vivo pump-probe microscopy of melanoma: characterizing shifts in excited state photodynamics with respect to invasiveness." SPIE BiOS.: SPIE, March 5, 2015. Full Text