Faculty Profiles

Steven Malcolmson
Assistant Professor of Chemistry
1103 French Science Center, Durham, NC 27708
(919) 660-1575
(919) 660-1605



Postdoctoral Fellow, Prof. Christopher Walsh, Harvard Medical School 2010 - 2013

Ph.D., Boston College 2010

B.A., Boston University 2004

Research Areas:
Synthesis, Inorganic, Organic

Colell, JFP, Emondts, M, Logan, AWJ, Shen, K, Bae, J, Shchepin, RV, Ortiz, GX, Spannring, P, Wang, Q, Malcolmson, SJ, Chekmenev, EY, Feiters, MC, Rutjes, FPJT, Blümich, B, Theis, T, and Warren, WS. "Direct Hyperpolarization of Nitrogen-15 in Aqueous Media with Parahydrogen in Reversible Exchange." Journal of the American Chemical Society 139.23 (June 2017): 7761-7767. Full Text

Adamson, NJ, Hull, E, and Malcolmson, SJ. "Enantioselective Intermolecular Addition of Aliphatic Amines to Acyclic Dienes with a Pd-PHOX Catalyst." Journal of the American Chemical Society 139.21 (May 2017): 7180-7183. Full Text

Colell, JFP, Logan, AWJ, Zhou, Z, Shchepin, RV, Barskiy, DA, Ortiz, GX, Wang, Q, Malcolmson, SJ, Chekmenev, EY, Warren, WS, and Theis, T. "Generalizing, Extending, and Maximizing Nitrogen-15 Hyperpolarization Induced by Parahydrogen in Reversible Exchange." The Journal of Physical Chemistry. C, Nanomaterials and Interfaces 121.12 (March 2017): 6626-6634. Full Text

Logan, AWJ, Theis, T, Colell, JFP, Warren, WS, and Malcolmson, SJ. "Hyperpolarization of Nitrogen-15 Schiff Bases by Reversible Exchange Catalysis with para-Hydrogen." Chemistry (Weinheim an Der Bergstrasse, Germany) 22.31 (July 2016): 10777-10781. Full Text

Theis, T, Ortiz, GX, Logan, AWJ, Claytor, KE, Feng, Y, Huhn, WP, Blum, V, Malcolmson, SJ, Chekmenev, EY, Wang, Q, and Warren, WS. "Direct and cost-efficient hyperpolarization of long-lived nuclear spin states on universal (15)N2-diazirine molecular tags." Science Advances 2.3 (March 25, 2016): e1501438-null. Full Text Open Access Copy

Malcolmson, SJ, Young, TS, Ruby, JG, Skewes-Cox, P, and Walsh, CT. "The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds." Proceedings of the National Academy of Sciences of the United States of America 110.21 (May 6, 2013): 8483-8488. Full Text

Lichtscheidl, AG, Ng, VWL, Müller, P, Takase, MK, Schrock, RR, Malcolmson, SJ, Meek, SJ, Li, B, Kiesewetter, ET, and Hoveyda, AH. "Bipyridine Adducts of Molybdenum Imido Alkylidene and Imido Alkylidyne Complexes." Organometallics 31.12 (June 6, 2012): 4558-4564. Full Text

Walsh, CT, Malcolmson, SJ, and Young, TS. "Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks." ACS Chem Biol 7.3 (March 16, 2012): 429-442. Full Text

Crawford, JM, Mahlstedt, SA, Malcolmson, SJ, Clardy, J, and Walsh, CT. "Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis." Chem Biol 18.9 (September 23, 2011): 1102-1112. Full Text

Zhang, W, Ntai, I, Bolla, ML, Malcolmson, SJ, Kahne, D, Kelleher, NL, and Walsh, CT. "Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics." J Am Chem Soc 133.14 (April 13, 2011): 5240-5243. Full Text