Faculty Profiles

Steven Malcolmson
Associate Professor of Chemistry
1103 French Science Center, Durham, NC 27708
(919) 660-1575
(919) 660-1605



Postdoctoral Fellow, Prof. Christopher Walsh, Harvard Medical School 2010 - 2013

Ph.D., Boston College 2010

B.A., Boston University 2004

Research Areas:
Synthesis, Inorganic, Organic

Adamson, Nathan J., et al. “Enantioselective Construction of Quaternary Stereogenic Centers by the Addition of an Acyl Anion Equivalent to 1,3-Dienes.Organic Letters, vol. 22, no. 5, Mar. 2020, pp. 2032–37. Epmc, doi:10.1021/acs.orglett.0c00412. Full Text

Adamson, N. J., and S. J. Malcolmson. “Catalytic Enantio- And Regioselective Addition of Nucleophiles in the Intermolecular Hydrofunctionalization of 1,3-Dienes.” Acs Catalysis, vol. 10, no. 2, Jan. 2020, pp. 1060–76. Scopus, doi:10.1021/acscatal.9b04712. Full Text

Shao, Xinxin, and Steven J. Malcolmson. “Catalytic Enantio- and Diastereoselective Cyclopropanation of 2-Azadienes for the Synthesis of Aminocyclopropanes Bearing Quaternary Carbon Stereogenic Centers.Organic Letters, vol. 21, no. 18, Sept. 2019, pp. 7380–85. Epmc, doi:10.1021/acs.orglett.9b02692. Full Text

Adamson, Nathan J., et al. “Preparation of Chiral Allenes through Pd-Catalyzed Intermolecular Hydroamination of Conjugated Enynes: Enantioselective Synthesis Enabled by Catalyst Design.Journal of the American Chemical Society, vol. 141, no. 21, May 2019, pp. 8574–83. Epmc, doi:10.1021/jacs.9b02637. Full Text

Park, Sangjune, et al. “Brønsted acid and Pd-PHOX dual-catalysed enantioselective addition of activated C-pronucleophiles to internal dienes.Chemical Science, vol. 10, no. 19, May 2019, pp. 5176–82. Epmc, doi:10.1039/c9sc00633h. Full Text

Malcolmson, S. J., et al. “2-Azadienes as Enamine Umpolung Synthons for the Preparation of Chiral Amines.” Synlett, vol. 30, no. 11, Jan. 2019, pp. 1253–68. Scopus, doi:10.1055/s-0037-1611770. Full Text

Park, S., and S. J. Malcolmson. “Development and Mechanistic Investigations of Enantioselective Pd-Catalyzed Intermolecular Hydroaminations of Internal Dienes.” Acs Catalysis, vol. 8, no. 9, Sept. 2018, pp. 8468–76. Scopus, doi:10.1021/acscatal.8b01914. Full Text

Adamson, Nathan J., et al. “Enantioselective Intermolecular Pd-Catalyzed Hydroalkylation of Acyclic 1,3-Dienes with Activated Pronucleophiles.Journal of the American Chemical Society, vol. 140, no. 8, Feb. 2018, pp. 2761–64. Epmc, doi:10.1021/jacs.7b13300. Full Text

Li, Kangnan, et al. “2-Azadienes as Reagents for Preparing Chiral Amines: Synthesis of 1,2-Amino Tertiary Alcohols by Cu-Catalyzed Enantioselective Reductive Couplings with Ketones.Journal of the American Chemical Society, vol. 140, no. 2, Jan. 2018, pp. 598–601. Epmc, doi:10.1021/jacs.7b12213. Full Text


Hoveyda, A. H., et al. “Catalyst-Controlled Stereoselective Olefin Metathesis.” Handbook of Metathesis: Second Edition, vol. 2–3, 2015, pp. 503–62. Scopus, doi:10.1002/9783527674107.ch21. Full Text