Ph.D., Stanford University 1973
B.S., Massachusetts Institute of Technology 1968
Friedman, HS, McLendon, RE, Kerby, T, Dugan, M, Bigner, SH, Henry, AJ, Ashley, DM, Krischer, J, Lovell, S, Rasheed, K, Marchev, F, Seman, AJ, Cokgor, I, Rich, J, Stewart, E, Colvin, OM, Provenzale, JM, Bigner, DD, Haglund, MM, Friedman, AH, and Modrich, PL. "DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 16.12 (December 1998): 3851-3857. Full Text
"Erratum: Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα (Journal of Biological Chemistry (1998) 273 (19895-19901))." Journal of Biological Chemistry 273.41 (October 9, 1998): 27034-null.
Veigl, ML, Kasturi, L, Olechnowicz, J, Ma, AH, Lutterbaugh, JD, Periyasamy, S, Li, GM, Drummond, J, Modrich, PL, Sedwick, WD, and Markowitz, SD. "Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers." Proceedings of the National Academy of Sciences of the United States of America 95.15 (July 1998): 8698-8702. Full Text
Lee, SE, Johnson, SP, Hale, LP, Li, J, Bullock, N, Fuchs, H, Friedman, A, McLendon, R, Bigner, DD, Modrich, P, and Friedman, HS. "Analysis of DNA mismatch repair proteins in human medulloblastoma." Clin Cancer Res 4.6 (June 1998): 1415-1419.
Hanley, ML, Elion, GB, Colvin, OM, Modrich, PL, Keir, S, Adams, DJ, Bigner, DD, and Friedman, HS. "Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors." Cancer Chemotherapy and Pharmacology 42.6 (January 1998): 479-482. Full Text
Genschel, J, Littman, SJ, Drummond, JT, and Modrich, P. "Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα." Journal of Biological Chemistry 273.31 (1998): 19895-19901. Full Text
Dao, V, and Modrich, P. "Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex." Journal of Biological Chemistry 273.15 (1998): 9202-9207. Full Text
Yamaguchi, M, Dao, V, and Modrich, P. "MutS and MutL activate DNA helicase II in a mismatch-dependent manner." Journal of Biological Chemistry 273.15 (1998): 9197-9201. Full Text
Eshleman, JR, Donover, PS, Littman, SJ, Swinler, SE, Li, G-M, Lutterbaugh, JD, Willson, JKV, Modrich, P, Sedwick, WD, Markowitz, SD, and Veigl, ML. "Increased transversions in a novel mutator colon cancer cell line." Oncogene 16.9 (1998): 1125-1130.
Nicolaides, NC, Littman, SJ, Modrich, P, Kinzler, KW, and Vogelstein, B. "A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype." Molecular and Cellular Biology 18.3 (1998): 1635-1641.