Faculty Profiles

Michael J. Therien
William R. Kenan, Jr. Distinguished Professor of Chemistry
5330 French Family Science Cen, Durham, NC 27708
(919) 660-1670
(919) 660-1605



NIH Postdoctoral Research Fellow, Chemistry, California Institute of Technology 1987 - 1990

Ph.D., University of California at San Diego 1987

B.S., University of St. Andrews (Scotland) 1982

Research Areas:
Synthesis, Physical, Biomolecular Structure and Function, Inorganic, Organic, Nanoscience and Materials

Kamat, Neha P., et al. “Sensing membrane stress with near IR-emissive porphyrins.Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 34, Aug. 2011, pp. 13984–89. Epmc, doi:10.1073/pnas.1102125108. Full Text

Susumu, Kimihiro, et al. “Two-photon absorption properties of proquinoidal D-A-D and A-D-A quadrupolar chromophores.The Journal of Physical Chemistry. A, vol. 115, no. 22, June 2011, pp. 5525–39. Epmc, doi:10.1021/jp2000738. Full Text

Guay, Daniel, et al. “Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists.Bioorganic & Medicinal Chemistry Letters, vol. 21, no. 10, May 2011, pp. 2832–35. Epmc, doi:10.1016/j.bmcl.2011.03.084. Full Text

Gauthier, Jacques Yves, et al. “The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14.Bioorganic & Medicinal Chemistry Letters, vol. 21, no. 10, May 2011, pp. 2836–39. Epmc, doi:10.1016/j.bmcl.2011.03.081. Full Text

Kang, Y. K., et al. “Electron transfer reactions of rigid, cofacially compressed, π-stacked porphyrin-bridge-quinone systems.” Coordination Chemistry Reviews, vol. 255, no. 7–8, Apr. 2011, pp. 804–24. Scopus, doi:10.1016/j.ccr.2010.12.011. Full Text

Lebedeva, Natalia V., et al. “Structural and pH dependence of excited state PCET reactions involving reductive quenching of the MLCT excited state of [RuII(bpy)2(bpz)]2+ by hydroquinones.The Journal of Physical Chemistry. A, vol. 115, no. 15, Apr. 2011, pp. 3346–56. Epmc, doi:10.1021/jp200381n. Full Text

Singh-Rachford, T. N., et al. “Erratum: Supermolecular-chromophore-sensitized near-infrared-to-visible photon upconversion (Journal of the American Chemical Society (2010) 132 (14203-14211) DOI: 10.1021/ja105510k).” Journal of the American Chemical Society, vol. 133, no. 8, Mar. 2011. Scopus, doi:10.1021/ja200045y. Full Text

Ishizuka, Tomoya, et al. “The roles of molecular structure and effective optical symmetry in evolving dipolar chromophoric building blocks to potent octopolar nonlinear optical chromophores.Journal of the American Chemical Society, vol. 133, no. 9, Mar. 2011, pp. 2884–96. Epmc, doi:10.1021/ja105004k. Full Text

Isabel, Elise, et al. “Difluoroethylamines as an amide isostere in inhibitors of cathepsin K.Bioorganic & Medicinal Chemistry Letters, vol. 21, no. 3, Feb. 2011, pp. 920–23. Epmc, doi:10.1016/j.bmcl.2010.12.070. Full Text

Robbins, Gregory P., et al. “Effects of Membrane Rheology on Leuko-polymersome Adhesion to Inflammatory Ligands.Soft Matter, vol. 7, no. 2, Jan. 2011, pp. 769–79. Epmc, doi:10.1039/C0SM00554A. Full Text