Faculty Profiles

Michael J. Therien
William R. Kenan, Jr. Distinguished Professor of Chemistry
5330 French Family Science Cen, Durham, NC 27708
(919) 660-1670
(919) 660-1605



NIH Postdoctoral Research Fellow, Chemistry, California Institute of Technology 1987 - 1990

Ph.D., University of California - San Diego 1987

B.S., University of St. Andrews (United Kingdom) 1982

Research Areas:
Synthesis, Physical, Biomolecular Structure and Function, Inorganic, Organic, Nanoscience and Materials

Hutchinson, J. H., et al. “Formation of a novel thiopyranoindole ring system.” Tetrahedron Letters, vol. 33, no. 33, Aug. 1992, pp. 4713–16. Scopus, doi:10.1016/S0040-4039(00)61266-2. Full Text

Evans, J. F., et al. “5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors.Molecular Pharmacology, vol. 40, no. 1, July 1991, pp. 22–27.

Prasit, P., et al. “A new class of leukotriene biosynthesis inhibitors: The development of ((4-(4-chlorophenyl)-1-(4-(2-quinolinylmethoxy)phenyl)butyl)thio)acetic acid, L-674,636.” Bioorganic and Medicinal Chemistry Letters, vol. 1, no. 11, Jan. 1991, pp. 645–48. Scopus, doi:10.1016/S0960-894X(01)81169-0. Full Text

Miller, G. A., et al. “Electrochemical studies of an oxidatively induced ring slippage in 17-electron (η3-indenyl)(η5-indenyl)V(CO)2.” Journal of Organometallic Chemistry, vol. 383, no. 1–3, Feb. 1990, pp. 271–78. Scopus, doi:10.1016/0022-328X(90)85136-M. Full Text

Therien, M. J., et al. “Long-Range Electron Transfer in Ruthenium-Modified Cytochrome c: Evaluation of Porphyrin-Ruthenium Electronic Couplings in the Candida krusei and Horse Heart Proteins.” Journal of the American Chemical Society, vol. 112, no. 6, Jan. 1990, pp. 2420–22. Scopus, doi:10.1021/ja00162a054. Full Text

Gauthier, J. Y., et al. “A novel and efficient method for the preparation of asymmetric dithioacetals.” Tetrahedron Letters, vol. 29, no. 51, Jan. 1988, pp. 6729–32. Scopus, doi:10.1016/S0040-4039(00)82440-5. Full Text

Thérien, M., et al. “Asymmetric dithioacetals II: A novel and versatile method for the preparation of chiral dithioacetals.” Tetrahedron Letters, vol. 29, no. 51, Jan. 1988, pp. 6733–36. Scopus, doi:10.1016/S0040-4039(00)82441-7. Full Text