Faculty Profiles

Michael J. Therien
William R. Kenan, Jr. Distinguished Professor of Chemistry
Office: 
5330 French Family Science Cen, Durham, NC 27708
Phone: 
(919) 660-1670
Fax: 
(919) 660-1605

Overview

Education:

NIH Postdoctoral Research Fellow, Chemistry, California Institute of Technology 1987 - 1990

Ph.D., University of California - San Diego 1987

B.S., University of St. Andrews (United Kingdom) 1982

Research Areas:
Synthesis, Physical, Biomolecular Structure and Function, Inorganic, Organic, Nanoscience and Materials

Hyslop, A. G., et al. “Suzuki porphyrins: New synthons for the fabrication of porphyrin- containing supramolecular assemblies [6].” Journal of the American Chemical Society, vol. 120, no. 48, Dec. 1998, pp. 12676–77. Scopus, doi:10.1021/ja982410h. Full Text

Kumble, R., et al. “Ultrafast dynamics of highly conjugated porphyrin arrays.” Journal of the American Chemical Society, vol. 120, no. 44, Nov. 1998, pp. 11489–98. Scopus, doi:10.1021/ja981811u. Full Text

Karki, L., et al. “Electronic stark effect studies of a porphyrin-based push-pull chromophore displaying a large first hyperpolarizability: State-specific contributions to β.” Journal of the American Chemical Society, vol. 120, no. 11, Mar. 1998, pp. 2606–11. Scopus, doi:10.1021/ja973593v. Full Text

Chan, C. C., et al. “A selective inhibitor of cyclooxygenase-2 reverses endotoxin-induced pyretic responses in non-human primates.European Journal of Pharmacology, vol. 327, no. 2–3, May 1997, pp. 221–25. Epmc, doi:10.1016/s0014-2999(97)89664-1. Full Text

Riendeau, D., et al. “Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.British Journal of Pharmacology, vol. 121, no. 1, May 1997, pp. 105–17. Epmc, doi:10.1038/sj.bjp.0701076. Full Text

Thérien, M., et al. “Synthesis and biological evaluation of 5,6-diarylimidazo[2.1-b]thiazole as selective COX-2 inhibitors.” Bioorganic and Medicinal Chemistry Letters, vol. 7, no. 1, Jan. 1997, pp. 47–52. Scopus, doi:10.1016/S0960-894X(96)00580-X. Full Text

Roy, P., et al. “A new series of selective COX-2 inhibitors: 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles.” Bioorganic and Medicinal Chemistry Letters, vol. 7, no. 1, Jan. 1997, pp. 57–62. Scopus, doi:10.1016/S0960-894X(96)00582-3. Full Text

Moore, K. T., et al. “High-pressure NMR studies of (porphinato)iron-catalyzed isobutane oxidation utilizing dioxygen as the stoichiometric oxidant.” Journal of the American Chemical Society, vol. 119, no. 7, Jan. 1997, pp. 1791–92. Scopus, doi:10.1021/ja961531j. Full Text

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