Faculty Profiles

Michael J. Therien
William R. Kenan, Jr. Professor of Chemistry in Trinity College of Arts and Sciences
5330 French Family Science Cen, Durham, NC 27708
(919) 660-1670
(919) 660-1605



NIH Postdoctoral Research Fellow, Chemistry, California Institute of Technology 1987 - 1990

Ph.D., University of California at San Diego 1987

B.S., University of St. Andrews (Scotland) 1982

Research Areas:
Synthesis, Physical, Biomolecular Structure and Function, Inorganic, Organic, Nanoscience and Materials

Thérien, M, Gauthier, J, and Young, R. "Asymmetric dithioacetals II: A novel and versatile method for the preparation of chiral dithioacetals." Tetrahedron Letters 29.51 (1988): 6733-6736. Full Text

Girard, Y, Hamel, P, Therien, M, Springer, JP, and Hirshfield, J. "First synthesis of sulfoxides and sulfones in the 3H-phenothiazin-3-one and 5H-benzo[a]phenothiazin-5-one ring systems. Addition reactions with nucleophiles." The Journal of Organic Chemistry 52.18 (September 1987): 4000-4006. Full Text

Guindon, Y, Therien, M, Girard, Y, and Yoakim, C. "Regiocontrolled opening of cyclic ethers using dimethylboron bromide." The Journal of Organic Chemistry 52.9 (May 1987): 1680-1686. Full Text

Firth, S, Hodge, PM, Poliakoff, M, Turner, JJ, and Therien, MJ. "Selective loss of CO in the photochemistry of MnRe(CO)10: a study using matrix isolation and time-resolved infrared spectroscopy." Journal of Organometallic Chemistry 331.3 (1987): 347-355. Full Text

Therien, MJ, and Trogler, WC. "Mechanism of oxidatively induced migratory insertion of carbon monoxide. Evidence for a 19-electron intermediate." Journal of the American Chemical Society 109.17 (1987): 5127-5133.

Therien, MJ, and Trogler, WC. "Tricarbonylbis(phosphine)iron(I) cation radicals. A spectroscopic and theoretical study." Journal of the American Chemical Society 108.13 (1986): 3697-3702.

Therien, MJ, Ni, C-L, Anson, FC, Osteryoung, JG, and Trogler, WC. "Kinetics of disproportionation of tricarbonylbis(phosphine)iron(I) cation radicals probed by double potential step chronocoulometry." Journal of the American Chemical Society 108.14 (1986): 4037-4042.

Hagopian, RA, Therien, MJ, and Murdoch, JR. "Synthesis of amines through nucleophilic addition on nitrogen." Journal of the American Chemical Society 106.19 (1984): 5753-5754.

Hanessian, S, Ugolini, A, and Therien, M. "Stereocontrolled synthesis of the spiro ketal unit of avermectin B1a aglycon." The Journal of Organic Chemistry 48.23 (November 1983): 4427-4430. Full Text

Hanessian, S, Roy, R, Therien, M, and Delorme, D. "Synthesis of 4-amino-4(S)-dihydrospectinomycin." The Journal of antibiotics 34.3 (March 1981): 350-352.