Faculty Profiles

Michael D Lynch
Assistant Professor in the Department of Biomedical Engineering

Overview

Education:

M.D., University of Colorado School of Medicine 2007

Ph.D., University of Colorado at Boulder 2005

Menacho-Melgar, R, Decker, JS, Hennigan, JN, and Lynch, MD. "A review of lipidation in the development of advanced protein and peptide therapeutics." Journal of Controlled Release : Official Journal of the Controlled Release Society 295 (February 2019): 1-12. (Review) Full Text

Moreb, EA, Hoover, B, Yaseen, A, Valyasevi, N, Roecker, Z, Menacho-Melgar, R, and Lynch, MD. "Managing the SOS Response for Enhanced CRISPR-Cas-Based Recombineering in E. coli through Transient Inhibition of Host RecA Activity." Acs Synthetic Biology 6.12 (December 2017): 2209-2218. Full Text

Burg, JM, Cooper, CB, Ye, Z, Reed, BR, Moreb, EA, and Lynch, MD. "Large-scale bioprocess competitiveness: the potential of dynamic metabolic control in two-stage fermentations." Current Opinion in Chemical Engineering 14 (November 1, 2016): 121-136. (Review) Full Text

Lynch, MD. "Into new territory: improved microbial synthesis through engineering of the essential metabolic network." Current Opinion in Biotechnology 38 (April 2016): 106-111. (Review) Full Text

Boyle, NR, Reynolds, TS, Evans, R, Lynch, M, and Gill, RT. "Recombineering to homogeneity: extension of multiplex recombineering to large-scale genome editing." Biotechnology Journal 8.5 (May 2013): 515-522. (Review) Full Text

Garst, A, Lynch, M, Evans, R, and Gill, RT. "Strategies for the multiplex mapping of genes to traits." Microbial Cell Factories 12 (January 2013): 99-null. (Review) Full Text

Warnecke, TE, Lynch, MD, Lipscomb, ML, and Gill, RT. "Identification of a 21 amino acid peptide conferring 3-hydroxypropionic acid stress-tolerance to Escherichia coli." Biotechnology and Bioengineering 109.5 (May 2012): 1347-1352. (Letter) Full Text

Prior, JE, Lynch, MD, and Gill, RT. "Broad-host-range vectors for protein expression across gram negative hosts." Biotechnology and Bioengineering 106.2 (June 2010): 326-332. Full Text

Warnecke, TE, Lynch, MD, Karimpour-Fard, A, Lipscomb, ML, Handke, P, Mills, T, Ramey, CJ, Hoang, T, and Gill, RT. "Rapid dissection of a complex phenotype through genomic-scale mapping of fitness altering genes." Metabolic Engineering 12.3 (May 2010): 241-250. Full Text

Singh, A, Lynch, MD, and Gill, RT. "Genes restoring redox balance in fermentation-deficient E. coli NZN111." Metabolic Engineering 11.6 (November 2009): 347-354. Full Text

Pages

Lipscomb, TW, Lipscomb, ML, Gill, RT, and Lynch, MD. "Metabolic Engineering of Recombinant E. coli for the Production of 3-Hydroxypropionate." Engineering Complex Phenotypes in Industrial Strains. October 24, 2012. 185-120. Full Text

Watson, FD, Mercogliano, CP, Ribble, WK, Anderson, RD, Liao, HH, Lipscomb, TW, and Lynch, MD. "Enzyme engineering of malonyl coA reductase (MCR) to improve 3-hydroxypropionate (3HP) production." 11th International Biorelated Polymer Symposium / 243rd National Spring Meeting of the American-Chemical-Society (ACS). March 25, 2012 - March 29, 2012. San Diego, CA.: AMER CHEMICAL SOC, March 25, 2012.

Lipscomb, ML, Lipscomb, TW, Liao, H, Maness, P, and Lynch, MD. "Production of fungible diesel via fatty acid synthesis from hydrogen and carbon dioxide feedstocks." 11th International Biorelated Polymer Symposium / 243rd National Spring Meeting of the American-Chemical-Society (ACS). March 25, 2012 - March 29, 2012. San Diego, CA.: AMER CHEMICAL SOC, March 25, 2012.

Lynch, MD, Manness, PC, Lipscomb, M, Warnecke, T, and Liao, H. "Novel biological conversion of hydrogen and carbon dioxide directly into biodiesel." December 1, 2011.

Lipscomb, ML, Warnecke, T, Hans, L, Maness, LP, and Lynch, MD. "Novel biological conversion of hydrogen and carbon dioxide directly into biodiesel." August 25, 2011.

Mercogliano, CP, Liao, HH, and Lynch, MD. "Enzyme evolution of an alpha-keto decarboxylase." 241st National Meeting and Exposition of the American-Chemical-Society (ACS). March 27, 2011 - March 31, 2011. Anaheim, CA.: AMER CHEMICAL SOC, March 27, 2011.

Lynch, MD, Warnecke, T, Singh, A, and Gill, RT. "Genomics tools for elucidating the function of trait conferring genes." December 1, 2005.

Warnecke, TE, Lynch, MD, and Gill, RT. "Post-genomics approach to understanding E. Coli network architecture." 229th National Meeting of the American-Chemical-Society. March 13, 2005 - March 17, 2005. San Diego, CA.: AMER CHEMICAL SOC, March 13, 2005.

Lynch, MD, Warnecke, T, and Gill, RT. "Mixed-library parallel gene trait mapping: A quantitative micro-array technique for the genome-wide identification of trait conferring genes." 229th National Meeting of the American-Chemical-Society. March 13, 2005 - March 17, 2005. San Diego, CA.: AMER CHEMICAL SOC, March 13, 2005.