Faculty Profiles

Michael D Lynch
Assistant Professor in the Department of Biomedical Engineering

Overview

Education:

M.D., University of Colorado School of Medicine 2007

Ph.D., University of Colorado at Boulder 2005

Menacho-Melgar, Romel, et al. “A review of lipidation in the development of advanced protein and peptide therapeutics..” Journal of Controlled Release : Official Journal of the Controlled Release Society, vol. 295, Feb. 2019, pp. 1–12. Epmc, doi:10.1016/j.jconrel.2018.12.032. Full Text

Moreb, Eirik Adim, et al. “Managing the SOS Response for Enhanced CRISPR-Cas-Based Recombineering in E. coli through Transient Inhibition of Host RecA Activity..” Acs Synthetic Biology, vol. 6, no. 12, Dec. 2017, pp. 2209–18. Epmc, doi:10.1021/acssynbio.7b00174. Full Text

Burg, J. M., et al. “Large-scale bioprocess competitiveness: the potential of dynamic metabolic control in two-stage fermentations.” Current Opinion in Chemical Engineering, vol. 14, Nov. 2016, pp. 121–36. Scopus, doi:10.1016/j.coche.2016.09.008. Full Text

Lynch, Michael D. “Into new territory: improved microbial synthesis through engineering of the essential metabolic network..” Current Opinion in Biotechnology, vol. 38, Apr. 2016, pp. 106–11. Epmc, doi:10.1016/j.copbio.2016.01.009. Full Text

Boyle, Nanette R., et al. “Recombineering to homogeneity: extension of multiplex recombineering to large-scale genome editing..” Biotechnology Journal, vol. 8, no. 5, May 2013, pp. 515–22. Epmc, doi:10.1002/biot.201200237. Full Text

Garst, Andrew, et al. “Strategies for the multiplex mapping of genes to traits..” Microbial Cell Factories, vol. 12, Jan. 2013. Epmc, doi:10.1186/1475-2859-12-99. Full Text

Warnecke, T. E., et al. “Identification of a 21 amino acid peptide conferring 3-hydroxypropionic acid stress-tolerance to Escherichia coli..” Biotechnology and Bioengineering, vol. 109, no. 5, May 2012, pp. 1347–52. Epmc, doi:10.1002/bit.24398. Full Text

Prior, Jamie E., et al. “Broad-host-range vectors for protein expression across gram negative hosts..” Biotechnology and Bioengineering, vol. 106, no. 2, June 2010, pp. 326–32. Epmc, doi:10.1002/bit.22695. Full Text

Warnecke, T. E., et al. “Rapid dissection of a complex phenotype through genomic-scale mapping of fitness altering genes..” Metabolic Engineering, vol. 12, no. 3, May 2010, pp. 241–50. Epmc, doi:10.1016/j.ymben.2009.12.002. Full Text

Singh, Amarjeet, et al. “Genes restoring redox balance in fermentation-deficient E. coli NZN111..” Metabolic Engineering, vol. 11, no. 6, Nov. 2009, pp. 347–54. Epmc, doi:10.1016/j.ymben.2009.07.002. Full Text

Pages

Lipscomb, T. W., et al. “Metabolic Engineering of Recombinant E. coli for the Production of 3-Hydroxypropionate.” Engineering Complex Phenotypes in Industrial Strains, 2012, pp. 185–120. Scopus, doi:10.1002/9781118433034.ch7. Full Text

Lynch, M. D. “A rational microbial design perspective in the design build test era.” Metabolic Engineering X, 2014, pp. 505–28.

Watson, Faith D., et al. “Enzyme engineering of malonyl coA reductase (MCR) to improve 3-hydroxypropionate (3HP) production.” Abstracts of Papers of the American Chemical Society, vol. 243, AMER CHEMICAL SOC, 2012.

Lipscomb, Matthew L., et al. “Production of fungible diesel via fatty acid synthesis from hydrogen and carbon dioxide feedstocks.” Abstracts of Papers of the American Chemical Society, vol. 243, AMER CHEMICAL SOC, 2012.

Lynch, M. D., et al. “Novel biological conversion of hydrogen and carbon dioxide directly into biodiesel.” Acs National Meeting Book of Abstracts, 2011.

Lipscomb, M. L., et al. “Novel biological conversion of hydrogen and carbon dioxide directly into biodiesel.” Acs National Meeting Book of Abstracts, 2011.

Mercogliano, Christopher P., et al. “Enzyme evolution of an alpha-keto decarboxylase.” Abstracts of Papers of the American Chemical Society, vol. 241, AMER CHEMICAL SOC, 2011.

Lynch, M. D., et al. “Genomics tools for elucidating the function of trait conferring genes.” Aiche Annual Meeting, Conference Proceedings, 2005.

Warnecke, T., et al. “Identification of organic acid tolerance genes in E. coli for biorefinery applications.” Aiche Annual Meeting, Conference Proceedings, 2005.

Warnecke, T. E., et al. “Post-genomics approach to understanding E. Coli network architecture..” Abstracts of Papers of the American Chemical Society, vol. 229, AMER CHEMICAL SOC, 2005, pp. U227–U227.

Lynch, M. D., et al. “Mixed-library parallel gene trait mapping: A quantitative micro-array technique for the genome-wide identification of trait conferring genes..” Abstracts of Papers of the American Chemical Society, vol. 229, AMER CHEMICAL SOC, 2005, pp. U202–U202.