Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Fitzgerald, M. C., et al. “Chapter 6 Thermodynamic Analysis of Protein Folding and Ligand Binding by SUPREX.” Comprehensive Analytical Chemistry, vol. 52, Dec. 2008, pp. 127–49. Scopus, doi:10.1016/S0166-526X(08)00206-7. Full Text

Hopper, Erin D., et al. “In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase..” The Journal of Biological Chemistry, vol. 283, no. 45, Nov. 2008, pp. 30493–502. Epmc, doi:10.1074/jbc.M803525200. Full Text

Hopper, Erin D., et al. “Throughput and efficiency of a mass spectrometry-based screening assay for protein-ligand binding detection..” J Am Soc Mass Spectrom, vol. 19, no. 9, Sept. 2008, pp. 1303–11. Pubmed, doi:10.1016/j.jasms.2008.06.007. Full Text

Weaver, Katherine D., et al. “Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA..” Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry, vol. 13, no. 6, Aug. 2008, pp. 887–98. Epmc, doi:10.1007/s00775-008-0376-5. Full Text

West, Graham M., et al. “Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy..” Analytical Chemistry, vol. 80, no. 11, June 2008, pp. 4175–85. Epmc, doi:10.1021/ac702610a. Full Text

Roulhac, Petra L., et al. “Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria..” Biochemistry, vol. 47, no. 14, Apr. 2008, pp. 4298–305. Epmc, doi:10.1021/bi701188x. Full Text

Weaver, K. D., et al. “Ga3+ as a mechanistic probe in Fe3+ transport: Characterization of Ga3+ interaction with FbpA.” Journal of Biological Inorganic Chemistry, vol. 13, no. 6, 2008, pp. 887–98. Scival, doi:10.1007/s00775-008-0376-5. Full Text

Tang, Liangjie, et al. “H/D exchange and mass spectrometry-based method for biophysical analysis of multidomain proteins at the domain level..” Analytical Chemistry, vol. 79, no. 22, Nov. 2007, pp. 8728–39. Epmc, doi:10.1021/ac071380a. Full Text

Tang, Liangjie, et al. “H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding..” Analytical Chemistry, vol. 79, no. 15, Aug. 2007, pp. 5869–77. Epmc, doi:10.1021/ac0700777. Full Text

Williams, John C., et al. “Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex..” Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 24, June 2007, pp. 10028–33. Epmc, doi:10.1073/pnas.0703614104. Full Text