Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
Office: 
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1547
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Cabrera, Aurora, et al. “Are allergens more abundant and/or more stable than other proteins in pollens and dust?Allergy, vol. 75, no. 5, May 2020, pp. 1267–69. Epmc, doi:10.1111/all.14121. Full Text

Lu, Kuan-Yi, et al. “Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy.Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 11, Mar. 2020, pp. 5810–17. Epmc, doi:10.1073/pnas.1913525117. Full Text

Cabrera, Aurora, et al. “Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach.Journal of the American Society for Mass Spectrometry, vol. 31, no. 2, Feb. 2020, pp. 217–26. Epmc, doi:10.1021/jasms.9b00041. Full Text

Ma, Renze, et al. “Chemo-Selection Strategy for Limited Proteolysis Experiments on the Proteomic Scale.Analytical Chemistry, vol. 90, no. 23, Dec. 2018, pp. 14039–47. Epmc, doi:10.1021/acs.analchem.8b04122. Full Text

Kaur, Upneet, et al. “Proteome-Wide Structural Biology: An Emerging Field for the Structural Analysis of Proteins on the Proteomic Scale.Journal of Proteome Research, vol. 17, no. 11, Nov. 2018, pp. 3614–27. Epmc, doi:10.1021/acs.jproteome.8b00341. Full Text

Meng, He, et al. “Chemical Denaturation and Protein Precipitation Approach for Discovery and Quantitation of Protein-Drug Interactions.Analytical Chemistry, vol. 90, no. 15, Aug. 2018, pp. 9249–55. Epmc, doi:10.1021/acs.analchem.8b01772. Full Text

Meng, He, and Michael C. Fitzgerald. “Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer.Journal of Proteome Research, vol. 17, no. 3, Mar. 2018, pp. 1129–37. Epmc, doi:10.1021/acs.jproteome.7b00795. Full Text

Ogburn, Ryenne N., et al. “Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements.Journal of Proteome Research, vol. 16, no. 11, Nov. 2017, pp. 4073–85. Epmc, doi:10.1021/acs.jproteome.7b00442. Full Text

Liu, Fang, et al. “Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX.Journal of Proteome Research, vol. 16, no. 9, Sept. 2017, pp. 3277–86. Epmc, doi:10.1021/acs.jproteome.7b00283. Full Text

Lim, Kwang Hun, et al. “Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation.Biochemistry, vol. 56, no. 36, Sept. 2017, pp. 4808–18. Epmc, doi:10.1021/acs.biochem.7b00658. Full Text

Pages