Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Ma, R, Meng, H, Wiebelhaus, N, and Fitzgerald, MC. "Chemo-Selection Strategy for Limited Proteolysis Experiments on the Proteomic Scale." Analytical Chemistry 90.23 (December 2018): 14039-14047. Full Text

Kaur, U, Meng, H, Lui, F, Ma, R, Ogburn, RN, Johnson, JHR, Fitzgerald, MC, and Jones, LM. "Proteome-Wide Structural Biology: An Emerging Field for the Structural Analysis of Proteins on the Proteomic Scale." Journal of Proteome Research 17.11 (November 2018): 3614-3627. Full Text

Meng, H, Ma, R, and Fitzgerald, MC. "Chemical Denaturation and Protein Precipitation Approach for Discovery and Quantitation of Protein-Drug Interactions." Analytical Chemistry 90.15 (August 2018): 9249-9255. Full Text

Meng, H, and Fitzgerald, MC. "Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer." Journal of Proteome Research 17.3 (March 2018): 1129-1137. Full Text

Ogburn, RN, Jin, L, Meng, H, and Fitzgerald, MC. "Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements." Journal of Proteome Research 16.11 (November 2017): 4073-4085. Full Text

Liu, F, Meng, H, and Fitzgerald, MC. "Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX." Journal of Proteome Research 16.9 (September 2017): 3277-3286. Full Text

Lim, KH, Dasari, AKR, Ma, R, Hung, I, Gan, Z, Kelly, JW, and Fitzgerald, MC. "Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation." Biochemistry 56.36 (September 2017): 4808-4818. Full Text

Randall, TA, London, RE, Fitzgerald, MC, and Mueller, GA. "Proteases of Dermatophagoides pteronyssinus." International journal of molecular sciences 18.6 (June 6, 2017). Full Text

Ogburn, RN, Randall, TA, Xu, Y, Roberts, JH, Mebrahtu, B, Karnuta, JM, Rider, SD, Kissling, GE, London, RE, Pomés, A, Arlian, L, Fitzgerald, MC, and Mueller, GA. "Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?." The Journal of Allergy and Clinical Immunology 139.3 (March 2017): 1030-1032.e1. Full Text

Roberts, JH, Liu, F, Karnuta, JM, and Fitzgerald, MC. "Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome." Journal of Proteome Research 15.12 (December 2016): 4731-4741. Full Text