Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Ma, Renze, et al. “Chemo-Selection Strategy for Limited Proteolysis Experiments on the Proteomic Scale..” Analytical Chemistry, vol. 90, no. 23, Dec. 2018, pp. 14039–47. Epmc, doi:10.1021/acs.analchem.8b04122. Full Text

Kaur, Upneet, et al. “Proteome-Wide Structural Biology: An Emerging Field for the Structural Analysis of Proteins on the Proteomic Scale..” Journal of Proteome Research, vol. 17, no. 11, Nov. 2018, pp. 3614–27. Epmc, doi:10.1021/acs.jproteome.8b00341. Full Text

Meng, He, et al. “Chemical Denaturation and Protein Precipitation Approach for Discovery and Quantitation of Protein-Drug Interactions..” Analytical Chemistry, vol. 90, no. 15, Aug. 2018, pp. 9249–55. Epmc, doi:10.1021/acs.analchem.8b01772. Full Text

Meng, He, and Michael C. Fitzgerald. “Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer..” Journal of Proteome Research, vol. 17, no. 3, Mar. 2018, pp. 1129–37. Epmc, doi:10.1021/acs.jproteome.7b00795. Full Text

Ogburn, Ryenne N., et al. “Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements..” Journal of Proteome Research, vol. 16, no. 11, Nov. 2017, pp. 4073–85. Epmc, doi:10.1021/acs.jproteome.7b00442. Full Text

Liu, Fang, et al. “Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX..” Journal of Proteome Research, vol. 16, no. 9, Sept. 2017, pp. 3277–86. Epmc, doi:10.1021/acs.jproteome.7b00283. Full Text

Lim, Kwang Hun, et al. “Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation..” Biochemistry, vol. 56, no. 36, Sept. 2017, pp. 4808–18. Epmc, doi:10.1021/acs.biochem.7b00658. Full Text

Randall, Thomas A., et al. “Proteases of Dermatophagoides pteronyssinus..” International Journal of Molecular Sciences, vol. 18, no. 6, June 2017. Epmc, doi:10.3390/ijms18061204. Full Text

Ogburn, Ryenne N., et al. “Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?.” The Journal of Allergy and Clinical Immunology, vol. 139, no. 3, Mar. 2017, pp. 1030-1032.e1. Epmc, doi:10.1016/j.jaci.2016.08.016. Full Text

Roberts, Julia H., et al. “Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome..” Journal of Proteome Research, vol. 15, no. 12, Dec. 2016, pp. 4731–41. Epmc, doi:10.1021/acs.jproteome.6b00927. Full Text