Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
Office: 
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1547
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Powell, Kendall D., et al. “Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method..” Protein Science : A Publication of the Protein Society, vol. 11, no. 4, Apr. 2002, pp. 841–51. Epmc, doi:10.1110/ps.3820102. Full Text

Silinski, Peter, and Michael C. Fitzgerald. “A stable dimer in the pH-induced equilibrium unfolding of the homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT)..” Biochemistry, vol. 41, no. 13, Apr. 2002, pp. 4480–91. Epmc, doi:10.1021/bi011872w. Full Text

Wales, T. E., and M. C. Fitzgerald. “The energetic contribution of backbone--backbone hydrogen bonds to the thermodynamic stability of a hyperstable P22 Arc repressor mutant..” Journal of the American Chemical Society, vol. 123, no. 31, Aug. 2001, pp. 7709–10. Epmc, doi:10.1021/ja010775n. Full Text

Powell, K. D., and M. C. Fitzgerald. “Measurements of protein stability by H/D exchange and matrix-assisted laser desorption/ionization mass spectrometry using picomoles of material..” Analytical Chemistry, vol. 73, no. 14, July 2001, pp. 3300–04. Epmc, doi:10.1021/ac0100805. Full Text

Silinski, P., et al. “Guanidine-induced equilibrium unfolding of a homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT)..” Biochemistry, vol. 40, no. 14, Apr. 2001, pp. 4493–502. Epmc, doi:10.1021/bi002752b. Full Text

Wang, M. Z., and M. C. Fitzgerald. “A solid sample preparation method that reduces signal suppression effects in the MALDI analysis of peptides..” Analytical Chemistry, vol. 73, no. 3, Feb. 2001, pp. 625–31. Epmc, doi:10.1021/ac0009090. Full Text

Moss, J. A., et al. “Mapping tertiary interactions in protein folding reactions: a novel mass spectrometry- and chemical synthesis-based approach..” Fresenius’ Journal of Analytical Chemistry, vol. 369, no. 3–4, Feb. 2001, pp. 252–57.

Powell, K. D., and M. C. Fitzgerald. “High Sensitivity Measurements of Protein Stability by H/D Exchange and Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass spectrometry..” Analytical Chemistry, vol. 73, no. 14, 2001, pp. 3300–04.

Nakhle, B. M., et al. “Identification of an essential backbone amide bond in the folding and stability of a multimeric enzyme.” Journal of the American Chemical Society, vol. 122, no. 34, Aug. 2000.

Nakhle, B. M., et al. “Identification of an essential backbone amide bond in the folding and stability of a multimeric enzyme.” Journal of the American Chemical Society, vol. 122, no. 34, Aug. 2000, pp. 8105–11. Scopus, doi:10.1021/ja0006090. Full Text

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