Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
Office: 
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1547
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Wu, Zemin, et al. “Synthesis of tetrahydro-1,4-benzodiazepine-2-ones on hydrophilic polyamide SynPhase lanterns..” Journal of Combinatorial Chemistry, vol. 5, no. 2, Mar. 2003, pp. 166–71. Epmc, doi:10.1021/cc020057c. Full Text

Campa, M. J., et al. “Protein Expression Profiling Identifies MIF and Cyclophilin A as Potential Molecular Targets in Non-Small Cell Lung Cancer.” Cancer Research, vol. 63, no. 7, 2003, pp. 1652–56.

Powell, K. D., and M. C. Fitzgerald. “Quantitative determination of protein-peptide binding constants using a new, MALDI- and H/D-exchange based technique.” Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics, Dec. 2002, pp. 445–46.

Fitzgerald, M. C., et al. “A general mass spectrometry-based method for the quantitation of protein-ligand binding interactions in solution.” Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics, Dec. 2002, pp. 395–96.

Wang, M. Z., et al. “A fractionation protocol to reduce signal suppression effects in the MALDI analysis of blood proteins.” Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics, Dec. 2002, pp. 587–88.

Ma, L., et al. “A new H/D exchange- and MALDI-based assay for the quantitative analysis of protein-DNA interactions in solution.” Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics, Dec. 2002, pp. 471–72.

Ghaemmaghami, S., et al. “Quantitative protein stability measurement in living bacteria.” Proceedings 50th Asms Conference on Mass Spectrometry and Allied Topics, Dec. 2002, pp. 109–10.

Powell, Kendall D., et al. “A general mass spectrometry-based assay for the quantitation of protein-ligand binding interactions in solution..” J Am Chem Soc, vol. 124, no. 35, Sept. 2002, pp. 10256–57. Pubmed, doi:10.1021/ja026574g. Full Text

Silinski, Peter, and Michael C. Fitzgerald. “A stable dimer in the pH-induced equilibrium unfolding of the homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT)..” Biochemistry, vol. 41, no. 13, Apr. 2002, pp. 4480–91. Epmc, doi:10.1021/bi011872w. Full Text

Powell, Kendall D., et al. “Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method..” Protein Science : A Publication of the Protein Society, vol. 11, no. 4, Apr. 2002, pp. 841–51. Epmc, doi:10.1110/ps.3820102. Full Text

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