Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Dai, Susie Y., and Michael C. Fitzgerald. “Accuracy of SUPREX (stability of unpurified proteins from rates of H/D exchange) and MALDI mass spectrometry-derived protein unfolding free energies determined under non-EX2 exchange conditions..” Journal of the American Society for Mass Spectrometry, vol. 17, no. 11, Nov. 2006, pp. 1535–42. Epmc, doi:10.1016/j.jasms.2006.06.025. Full Text

Dai, Susie Y., and Michael C. Fitzgerald. “A mass spectrometry-based probe of equilibrium intermediates in protein-folding reactions..” Biochemistry, vol. 45, no. 42, Oct. 2006, pp. 12890–97. Epmc, doi:10.1021/bi061295h. Full Text

Yang, Xiaoye, et al. “Direct analysis of backbone-backbone hydrogen bond formation in protein folding transition states..” Journal of Molecular Biology, vol. 363, no. 2, Oct. 2006, pp. 506–19. Epmc, doi:10.1016/j.jmb.2006.07.058. Full Text

Yang, Xiaoye, and Michael C. Fitzgerald. “Total chemical synthesis of the B1 domain of protein L from Peptostreptococcus magnus..” Bioorganic Chemistry, vol. 34, no. 3, June 2006, pp. 131–41. Epmc, doi:10.1016/j.bioorg.2006.02.001. Full Text

Wang, Min, et al. “Conserved thermodynamic contributions of backbone hydrogen bonds in a protein fold..” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 8, Feb. 2006, pp. 2600–04. Epmc, doi:10.1073/pnas.0508121103. Full Text

Cisneros, G. Andrés, et al. “Theoretical and experimental determination on two substrates turned over by 4-oxalocrotonate tautomerase..” The Journal of Physical Chemistry. A, vol. 110, no. 2, Jan. 2006, pp. 700–08. Epmc, doi:10.1021/jp0543328. Full Text

Tong, Yan, et al. “Thermodynamic analysis of subunit interactions in Escherichia coli molybdopterin synthase..” Biochemistry, vol. 44, no. 7, Feb. 2005, pp. 2595–601. Epmc, doi:10.1021/bi047762h. Full Text

Dai, Susie Y., et al. “Protocol for the thermodynamic analysis of some proteins using an H/D exchange- and mass spectrometry-based technique..” Analytical Chemistry, vol. 77, no. 2, Jan. 2005, pp. 693–97. Epmc, doi:10.1021/ac048967z. Full Text

Wang, M., et al. “The Thermodynamics of Backbone-Backbone Hydrogen Bonds are Conserved ina Protein Fold.” Proceedings of the National Academy of Sciences, Usa, 2005.