Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Xu, Y., et al. “Xu, Y., Falk, I.N., Hallen, M.A., and Fitzgerald, M.C.Analytical Chemistry, no. 83, 2011, pp. 3555–62.

Dearmond, Patrick D., et al. “Discovery of novel cyclophilin A ligands using an H/D exchange- and mass spectrometry-based strategy.J Biomol Screen, vol. 15, no. 9, Oct. 2010, pp. 1051–62. Pubmed, doi:10.1177/1087057110382775. Full Text

Kim, Hyoungsu, et al. “Total synthesis, assignment of the absolute stereochemistry, and structure-activity relationship studies of subglutinols A and B.Chemistry, an Asian Journal, vol. 5, no. 8, Aug. 2010, pp. 1902–10. Epmc, doi:10.1002/asia.201000147. Full Text

West, Graham M., et al. “Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.Anal Chem, vol. 82, no. 13, July 2010, pp. 5573–81. Pubmed, doi:10.1021/ac100465a. Full Text Open Access Copy

West, Graham M., et al. “Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 20, May 2010, pp. 9078–82. Epmc, doi:10.1073/pnas.1000148107. Full Text

Xu, Ying, et al. “Thermodynamic analysis of a molecular chaperone binding to unfolded protein substrates.Biochemistry, vol. 49, no. 6, Feb. 2010, pp. 1346–53. Epmc, doi:10.1021/bi902010t. Full Text Open Access Copy

DeArmond, P. D., et al. “Discovery of Novel Cyclophilin A Ligands Using an H/D Exchange- and Mass Spectrometry-Based Strategy. Journal of Biomolecular Screening.Journal of Biomolecular Screening, vol. 15, no. 9, 2010, pp. 1051–62.

Hopper, Erin D., et al. “Hydrogen/deuterium exchange- and protease digestion-based screening assay for protein-ligand binding detection.Anal Chem, vol. 81, no. 16, Aug. 2009, pp. 6860–67. Pubmed, doi:10.1021/ac900854t. Full Text

Fitzgerald, Michael C., and Graham M. West. “Painting proteins with covalent labels: what's in the picture?Journal of the American Society for Mass Spectrometry, vol. 20, no. 6, June 2009, pp. 1193–206. Epmc, doi:10.1016/j.jasms.2009.02.006. Full Text

Siburt, Claire J. Parker, et al. “Hijacking transferrin bound iron: protein-receptor interactions involved in iron transport in N. gonorrhoeae.Metallomics : Integrated Biometal Science, vol. 1, no. 3, Jan. 2009, pp. 249–55. Epmc, doi:10.1039/b902860a. Full Text