Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
Office: 
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1547
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Fitzgerald, M. C., et al. “A Continuous Fluorometric Assay for the FIV Protease.” Analytical Biochemistry, vol. 254, no. 2, 1997, pp. 226–30.

Muir, T. W., et al. “Protein signature analysis: a practical new approach for studying structure-activity relationships in peptides and proteins..” Methods in Enzymology, vol. 289, Jan. 1997, pp. 545–64. Epmc, doi:10.1016/s0076-6879(97)89063-5. Full Text

Qian, X., et al. “C2-symmetrical tetrahydroxyazepanes as inhibitors of glycosidases and HIV/FIV proteases..” Bioorganic & Medicinal Chemistry, vol. 4, no. 12, Dec. 1996, pp. 2055–69. Epmc, doi:10.1016/s0968-0896(96)00218-0. Full Text

Muir, T. W., et al. “Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis..” Chemistry & Biology, vol. 3, no. 10, Oct. 1996, pp. 817–25. Epmc, doi:10.1016/s1074-5521(96)90067-8. Full Text

Fitzgerald, M. C., and G. Siuzdak. “Biochemical mass spectrometry: worth the weight?.” Chemistry & Biology, vol. 3, no. 9, Sept. 1996, pp. 707–15. Epmc, doi:10.1016/s1074-5521(96)90245-8. Full Text

Fitzgerald, M. C., et al. “Probing the oligomeric structure of an enzyme by electrospray ionization time-of-flight mass spectrometry..” Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 14, July 1996, pp. 6851–56. Epmc, doi:10.1073/pnas.93.14.6851. Full Text

Fitzgerald, M. C., et al. “Direct characterization of solid phase resin-bound molecules by mass spectrometry.” Bioorganic and Medicinal Chemistry Letters, vol. 6, no. 8, Apr. 1996, pp. 979–82. Scopus, doi:10.1016/0960-894X(96)00152-7. Full Text

Qian, X., et al. “C2-Symmetrical Tetrahydroxyazepenes as Inhibitors of Glyosidases and HIV/FIV Proteases.” Bioorganic & Medicinal Chemistry, vol. 4, no. 12, 1996, pp. 2055–69.

Zhu, L., et al. “Oligodeoxynucleotide Fragmentation in MALDI/TOF Mass Spectrometry Using 355-nm Radiation.” Journal of the American Chemical Society, vol. 117, no. 22, Jan. 1995, pp. 6048–56. Scopus, doi:10.1021/ja00127a018. Full Text

Fitzgerald, M. C., et al. “Total Chemical Synthesis and Catalytic Properties of the Enzyme Enantiomers L- and D-4-Oxalocrotonate Tautomerase.” Journal of the American Chemical Society, vol. 117, no. 45, Jan. 1995, pp. 11075–80. Scopus, doi:10.1021/ja00150a006. Full Text

Pages