Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
Office: 
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1547
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Muir, T. W., et al. “Protein signature analysis: a practical new approach for studying structure-activity relationships in peptides and proteins..” Methods in Enzymology, vol. 289, Jan. 1997, pp. 545–64. Epmc, doi:10.1016/s0076-6879(97)89063-5. Full Text

Qian, X., et al. “C2-symmetrical tetrahydroxyazepanes as inhibitors of glycosidases and HIV/FIV proteases..” Bioorganic & Medicinal Chemistry, vol. 4, no. 12, Dec. 1996, pp. 2055–69. Epmc, doi:10.1016/s0968-0896(96)00218-0. Full Text

Muir, T. W., et al. “Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis..” Chemistry & Biology, vol. 3, no. 10, Oct. 1996, pp. 817–25. Epmc, doi:10.1016/s1074-5521(96)90067-8. Full Text

Fitzgerald, M. C., and G. Siuzdak. “Biochemical mass spectrometry: worth the weight?.” Chemistry & Biology, vol. 3, no. 9, Sept. 1996, pp. 707–15. Epmc, doi:10.1016/s1074-5521(96)90245-8. Full Text

Fitzgerald, M. C., et al. “Probing the oligomeric structure of an enzyme by electrospray ionization time-of-flight mass spectrometry..” Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 14, July 1996, pp. 6851–56. Epmc, doi:10.1073/pnas.93.14.6851. Full Text

Fitzgerald, M. C., et al. “Direct characterization of solid phase resin-bound molecules by mass spectrometry.” Bioorganic and Medicinal Chemistry Letters, vol. 6, no. 8, Apr. 1996, pp. 979–82. Scopus, doi:10.1016/0960-894X(96)00152-7. Full Text

Qian, X., et al. “C2-Symmetrical Tetrahydroxyazepenes as Inhibitors of Glyosidases and HIV/FIV Proteases.” Bioorganic & Medicinal Chemistry, vol. 4, no. 12, 1996, pp. 2055–69.

Zhu, L., et al. “Oligodeoxynucleotide Fragmentation in MALDI/TOF Mass Spectrometry Using 355-nm Radiation.” Journal of the American Chemical Society, vol. 117, no. 22, Jan. 1995, pp. 6048–56. Scopus, doi:10.1021/ja00127a018. Full Text

Fitzgerald, M. C., et al. “Total Chemical Synthesis and Catalytic Properties of the Enzyme Enantiomers L- and D-4-Oxalocrotonate Tautomerase.” Journal of the American Chemical Society, vol. 117, no. 45, Jan. 1995, pp. 11075–80. Scopus, doi:10.1021/ja00150a006. Full Text

Fitzgerald, M. C., and L. M. Smith. “Mass spectrometry of nucleic acids: the promise of matrix-assisted laser desorption-ionization (MALDI) mass spectrometry..” Annual Review of Biophysics and Biomolecular Structure, vol. 24, Jan. 1995, pp. 117–40. Epmc, doi:10.1146/annurev.bb.24.060195.001001. Full Text

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