Faculty Profiles

Kevin D. Welsher
Assistant Professor of Chemistry
2213 French Science Center, Durham, NC 27705
(919) 660-1509
(919) 660-1605



Postdoctoral Associate, Chemistry, Princeton University 2010 - 2015

Ph.D., Stanford University 2010

B.Sc., Emory University 2005

Research Areas:
Physical, Nanoscience and Materials, Analytical

Patel, Siddharth, et al. “Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA.Nature Communications, vol. 11, no. 1, Feb. 2020, p. 983. Epmc, doi:10.1038/s41467-020-14527-2. Full Text

Johnson, Courtney, et al. “Continuous focal translation enhances rate of point-scan volumetric microscopy.Optics Express, vol. 27, no. 25, Dec. 2019, pp. 36241–58. Epmc, doi:10.1364/oe.27.036241. Full Text

Hou, Shangguo, and Kevin Welsher. “An Adaptive Real-Time 3D Single Particle Tracking Method for Monitoring Viral First Contacts.Small (Weinheim an Der Bergstrasse, Germany), vol. 15, no. 44, Oct. 2019, p. e1903039. Epmc, doi:10.1002/smll.201903039. Full Text

Hou, Shangguo, et al. “Real-Time 3D Single Particle Tracking: Towards Active Feedback Single Molecule Spectroscopy in Live Cells.Molecules (Basel, Switzerland), vol. 24, no. 15, Aug. 2019. Epmc, doi:10.3390/molecules24152826. Full Text

Hou, Shangguo, and Kevin Welsher. “A Protocol for Real-time 3D Single Particle Tracking.Journal of Visualized Experiments : Jove, no. 131, Jan. 2018. Epmc, doi:10.3791/56711. Full Text

Hou, Shangguo, et al. “Robust real-time 3D single-particle tracking using a dynamically moving laser spot.Optics Letters, vol. 42, no. 12, June 2017, pp. 2390–93. Epmc, doi:10.1364/ol.42.002390. Full Text

Welsher, Kevin, et al. “Discovery of protein- and DNA-imperceptible nanoparticle hard coating using gel-based reaction tuning.Journal of the American Chemical Society, vol. 137, no. 2, Jan. 2015, pp. 580–83. Epmc, doi:10.1021/ja511297d. Full Text

Welsher, Kevin, and Haw Yang. “Imaging the behavior of molecules in biological systems: breaking the 3D speed barrier with 3D multi-resolution microscopy.Faraday Discussions, vol. 184, Jan. 2015, pp. 359–79. Epmc, doi:10.1039/c5fd00090d. Full Text

Welsher, Kevin, and Haw Yang. “Multi-resolution 3D visualization of the early stages of cellular uptake of peptide-coated nanoparticles.Nature Nanotechnology, vol. 9, no. 3, Mar. 2014, pp. 198–203. Epmc, doi:10.1038/nnano.2014.12. Full Text

Welsher, K., and H. Yang. “Three-dimensional target-locking microscopy.” Optics Infobase Conference Papers, Jan. 2013.