Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry and Department Chair
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Dickens, MG, and Franz, KJ. "A prochelator activated by hydrogen peroxide prevents metal-induced amyloid Beta aggregation." Chembiochem 11.1 (January 4, 2010): 59-62. Full Text

Crider, SE, Holbrook, RJ, and Franz, KJ. "Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1." Metallomics : Integrated Biometal Science 2.1 (January 2010): 74-83. Full Text Open Access Copy

Franz, KJ, and He, C. "The highways and byways of bioinorganic chemistry." Current Opinion in Chemical Biology 14.2 (2010): 208-210. Full Text

Haas, KL, and Franz, KJ. "Application of metal coordination chemistry to explore and manipulate cell biology." Chemical Reviews 109.10 (October 2009): 4921-4960. (Review) Full Text

Palmer, AE, and Franz, KJ. "Introduction to cellular metal homeostasis and trafficking." Chemical Reviews 109.10 (2009): 4533-4535. Full Text

Charkoudian, LK, Dentchev, T, Lukinova, N, Wolkow, N, Dunaief, JL, and Franz, KJ. "Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide." J Inorg Biochem 102.12 (December 2008): 2130-2135. Full Text

Ciesienski, KL, Haas, KL, Dickens, MG, Tesema, YT, and Franz, KJ. "A photolabile ligand for light-activated release of caged copper." J Am Chem Soc 130.37 (September 17, 2008): 12246-12247. Full Text

Tesema, YT, Pham, DM, and Franz, KJ. "Counterions influence reactivity of metal ions with cysteinyldopa model compounds." Inorg Chem 47.3 (February 4, 2008): 1087-1095. Full Text

Franz, KJ. "Copper shares a piece of the π." Nature Chemical Biology 4.2 (2008): 85-86. Full Text

Charkoudian, LK, Pham, DM, Kwon, AM, Vangeloff, AD, and Franz, KJ. "Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress." Dalton Trans 43 (November 21, 2007): 5031-5042. Full Text