Faculty Profiles

Katherine J. Franz
Chair of the Department of Chemistry
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Bureš, Jan, et al. “LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)..” Journal of Pharmaceutical and Biomedical Analysis, vol. 105, Feb. 2015, pp. 55–63. Epmc, doi:10.1016/j.jpba.2014.11.044. Full Text

Safi, Rachid, et al. “Copper signaling axis as a target for prostate cancer therapeutics..” Cancer Res, vol. 74, no. 20, Oct. 2014, pp. 5819–31. Pubmed, doi:10.1158/0008-5472.CAN-13-3527. Full Text Open Access Copy

Franks, Andrew T., and Katherine J. Franz. “A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting..” Chemical Communications (Cambridge, England), vol. 50, no. 77, Oct. 2014, pp. 11317–20. Epmc, doi:10.1039/c4cc05076b. Full Text

Jansová, Hana, et al. “Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury..” Free Radical Biology & Medicine, vol. 74, Sept. 2014, pp. 210–21. Epmc, doi:10.1016/j.freeradbiomed.2014.06.019. Full Text

Festa, Richard A., et al. “Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection..” Chem Biol, vol. 21, no. 8, Aug. 2014, pp. 977–87. Pubmed, doi:10.1016/j.chembiol.2014.06.009. Full Text

Festa, R. A., et al. “Innate immune cell activation of a copper-dependent anti-cryptococcal agent.” Mycoses, vol. 57, WILEY-BLACKWELL, May 2014, pp. 56–57.

Franks, Andrew T., et al. “Characterization of a photoswitching chelator with light-modulated geometric, electronic, and metal-binding properties..” Inorganic Chemistry, vol. 53, no. 3, Feb. 2014, pp. 1397–405. Epmc, doi:10.1021/ic402221x. Full Text

Folk, D. S., et al. Bioinorganic Neurochemistry. Vol. 3, Aug. 2013, pp. 207–40. Scopus, doi:10.1016/B978-0-08-097774-4.00315-6. Full Text

Grant, Gerald A., et al. “The 62nd Annual Meeting of the Congress of Neurological Surgeons was held in Chicago, Illinois from October 6-10, 2012. Preface..” Neurosurgery, vol. 60 Suppl 1, Aug. 2013. Pubmed, doi:10.1227/NEU.0000000000000006. Full Text

Franz, Katherine J. “Clawing back: broadening the notion of metal chelators in medicine..” Current Opinion in Chemical Biology, vol. 17, no. 2, Apr. 2013, pp. 143–49. Epmc, doi:10.1016/j.cbpa.2012.12.021. Full Text


Liu, L. L., and K. J. Franz. “Characterization of metal binding sites in a synthetic phosphorylated alpha-synuclein peptide fragment..” Abstracts of Papers of the American Chemical Society, vol. 229, AMER CHEMICAL SOC, 2005, pp. U1080–81.

Franz, Katherine J., et al. “Development of lanthanide-binding peptides as natively expressed protein probes.” Journal of Inorganic Biochemistry, vol. 96, no. 1, Elsevier BV, 2003, pp. 131–131. Crossref, doi:10.1016/s0162-0134(03)80614-1. Full Text