Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Tesema, Yohannes T., et al. “Counterions influence reactivity of metal ions with cysteinyldopa model compounds..” Inorganic Chemistry, vol. 47, no. 3, Feb. 2008, pp. 1087–95. Epmc, doi:10.1021/ic701889w. Full Text

Franz, Katherine J. “Copper shares a piece of the pi..” Nature Chemical Biology, vol. 4, no. 2, Feb. 2008, pp. 85–86. Epmc, doi:10.1038/nchembio0208-85. Full Text

Charkoudian, Louise K., et al. “Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress..” Dalton Transactions (Cambridge, England : 2003), no. 43, Nov. 2007, pp. 5031–42. Epmc, doi:10.1039/b705199a. Full Text

Liu, Lucy L., and Katherine J. Franz. “Phosphorylation-dependent metal binding by alpha-synuclein peptide fragments..” Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry, vol. 12, no. 2, Feb. 2007, pp. 234–47. Epmc, doi:10.1007/s00775-006-0181-y. Full Text

Charkoudian, Louise K., et al. “A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation..” Journal of the American Chemical Society, vol. 128, no. 38, Sept. 2006, pp. 12424–25. Epmc, doi:10.1021/ja064806w. Full Text

Tesema, Yohannes T., et al. “Synthesis and characterization of copper(II) complexes of cysteinyldopa and benzothiazine model ligands related to pheomelanin..” Inorganic Chemistry, vol. 45, no. 16, Aug. 2006, pp. 6102–04. Epmc, doi:10.1021/ic060262n. Full Text

Charkoudian, Louise K., and Katherine J. Franz. “Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid..” Inorganic Chemistry, vol. 45, no. 9, May 2006, pp. 3657–64. Epmc, doi:10.1021/ic060014r. Full Text

Jiang, Jianfeng, et al. “A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination..” Inorganic Chemistry, vol. 44, no. 26, Dec. 2005, pp. 9787–94. Epmc, doi:10.1021/ic051180m. Full Text

Liu, Lucy L., and Katherine J. Franz. “Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding..” Journal of the American Chemical Society, vol. 127, no. 27, July 2005, pp. 9662–63. Epmc, doi:10.1021/ja043247v. Full Text

Nitz, Mark, et al. “Structural origin of the high affinity of a chemically evolved lanthanide-binding peptide..” Angewandte Chemie (International Ed. in English), vol. 43, no. 28, July 2004, pp. 3682–85. Epmc, doi:10.1002/anie.200460028. Full Text