Faculty Profiles

Katherine J. Franz
Professor in the Department of Chemistry
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Rubino, Jeffrey T., et al. “A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments.Metallomics : Integrated Biometal Science, vol. 3, no. 1, Jan. 2011, pp. 61–73. Epmc, doi:10.1039/c0mt00044b. Full Text

Ciesienski, Katie L., et al. “Development of next-generation photolabile copper cages with improved copper binding properties.Dalton Transactions (Cambridge, England : 2003), vol. 39, no. 40, Oct. 2010, pp. 9538–46. Epmc, doi:10.1039/c0dt00770f. Full Text Open Access Copy

Rubino, Jeffrey T., et al. “Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I).Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry, vol. 15, no. 7, Sept. 2010, pp. 1033–49. Epmc, doi:10.1007/s00775-010-0663-9. Full Text

Ciesienski, Katie L., et al. “Toward the detection of cellular copper(II) by a light-activated fluorescence increase.Inorganic Chemistry, vol. 49, no. 15, Aug. 2010, pp. 6808–10. Epmc, doi:10.1021/ic1004165. Full Text Open Access Copy

Ciesienski, K. L., et al. “A photo-caged platinum(II) complex that increases cytotoxicity upon light activation.” European Journal of Inorganic Chemistry, no. 15, May 2010, pp. 2224–28. Scopus, doi:10.1002/ejic.201000098. Full Text

Franz, Katherine J., and Chuan He. “The highways and byways of bioinorganic chemistry.Current Opinion in Chemical Biology, vol. 14, no. 2, Apr. 2010, pp. 208–10. Epmc, doi:10.1016/j.cbpa.2010.02.011. Full Text

Folk, Drew S., and Katherine J. Franz. “A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation.Journal of the American Chemical Society, vol. 132, no. 14, Apr. 2010, pp. 4994–95. Epmc, doi:10.1021/ja100943r. Full Text Open Access Copy

Perez, Lissette R., and Katherine J. Franz. “Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease.Dalton Transactions (Cambridge, England : 2003), vol. 39, no. 9, Mar. 2010, pp. 2177–87. Epmc, doi:10.1039/b919237a. Full Text Open Access Copy

Tangen, Espen, et al. “Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand.Inorganic Chemistry, vol. 49, no. 6, Mar. 2010, pp. 2701–05. Epmc, doi:10.1021/ic901860x. Full Text

Hyman, Lynne M., et al. “Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress.Dalton Transactions (Cambridge, England : 2003), no. 2, Jan. 2010, pp. 568–76. Epmc, doi:10.1039/b914568k. Full Text