Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Tangen, E, Conradie, J, Franz, K, Friedle, S, Telser, J, Lippard, SJ, and Ghosh, A. "Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand." Inorganic Chemistry 49.6 (March 2010): 2701-2705. Full Text

Hyman, LM, Stephenson, CJ, Dickens, MG, Shimizu, KD, and Franz, KJ. "Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress." Dalton Trans 2 (January 14, 2010): 568-576. Full Text

Dickens, MG, and Franz, KJ. "A prochelator activated by hydrogen peroxide prevents metal-induced amyloid Beta aggregation." Chembiochem 11.1 (January 4, 2010): 59-62. Full Text

Crider, SE, Holbrook, RJ, and Franz, KJ. "Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1." Metallomics : Integrated Biometal Science 2.1 (January 2010): 74-83. Full Text Open Access Copy

Franz, KJ, and He, C. "The highways and byways of bioinorganic chemistry." Current Opinion in Chemical Biology 14.2 (2010): 208-210. Full Text

Haas, KL, and Franz, KJ. "Application of metal coordination chemistry to explore and manipulate cell biology." Chemical Reviews 109.10 (October 2009): 4921-4960. (Review) Full Text

Palmer, AE, and Franz, KJ. "Introduction to cellular metal homeostasis and trafficking." Chemical Reviews 109.10 (2009): 4533-4535. Full Text

Charkoudian, LK, Dentchev, T, Lukinova, N, Wolkow, N, Dunaief, JL, and Franz, KJ. "Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide." J Inorg Biochem 102.12 (December 2008): 2130-2135. Full Text

Ciesienski, KL, Haas, KL, Dickens, MG, Tesema, YT, and Franz, KJ. "A photolabile ligand for light-activated release of caged copper." J Am Chem Soc 130.37 (September 17, 2008): 12246-12247. Full Text