Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Franz, KJ. "Clawing back: broadening the notion of metal chelators in medicine." Current Opinion in Chemical Biology 17.2 (April 2013): 143-149. (Review) Full Text

Kumbhar, AA, Franks, AT, Butcher, RJ, and Franz, KJ. "Light uncages a copper complex to induce nonapoptotic cell death." Chem Commun (Camb) 49.24 (March 25, 2013): 2460-2462. Full Text

Franz, KJ. "Clawing back: Broadening the notion of metal chelators in medicine." Current Opinion in Chemical Biology 17.2 (2013): 143-149. Full Text

Kielar, F, Wang, Q, Boyle, PD, and Franz, KJ. "A boronate prochelator built on a triazole framework for peroxide-triggered tridentate metal binding." Inorganica Chimica Acta 393 (December 2012): 294-303. Full Text

Folk, DS, Torosian, JC, Hwang, S, McCafferty, DG, and Franz, KJ. "Monitoring β-secretase activity in living cells with a membrane-anchored FRET probe." Angew Chem Int Ed Engl 51.43 (October 22, 2012): 10795-10799. Full Text

Hyman, LM, and Franz, KJ. "Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols." Coordination Chemistry Reviews 256.19-20 (October 2012): 2333-2356. Full Text

Kielar, F, Helsel, ME, Wang, Q, and Franz, KJ. "Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation." Metallomics : Integrated Biometal Science 4.9 (August 2012): 899-909. Full Text

Rubino, JT, and Franz, KJ. "Coordination chemistry of copper proteins: how nature handles a toxic cargo for essential function." Journal of Inorganic Biochemistry 107.1 (February 2012): 129-143. (Review) Full Text

Franz, KJ. "Application of inorganic chemistry for non-cancer therapeutics." Dalton Transactions 41.21 (2012): 6333-6334. Full Text