Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry
Office: 
2103 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1541

Overview

Education:

Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Folk, Drew S., and Katherine J. Franz. “A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation..” Journal of the American Chemical Society, vol. 132, no. 14, Apr. 2010, pp. 4994–95. Epmc, doi:10.1021/ja100943r. Full Text Open Access Copy

Perez, Lissette R., and Katherine J. Franz. “Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease..” Dalton Transactions (Cambridge, England : 2003), vol. 39, no. 9, Mar. 2010, pp. 2177–87. Epmc, doi:10.1039/b919237a. Full Text Open Access Copy

Tangen, Espen, et al. “Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand..” Inorganic Chemistry, vol. 49, no. 6, Mar. 2010, pp. 2701–05. Epmc, doi:10.1021/ic901860x. Full Text

Hyman, Lynne M., et al. “Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress..” Dalton Transactions (Cambridge, England : 2003), no. 2, Jan. 2010, pp. 568–76. Epmc, doi:10.1039/b914568k. Full Text

Dickens, Marina G., and Katherine J. Franz. “A prochelator activated by hydrogen peroxide prevents metal-induced amyloid Beta aggregation..” Chembiochem : A European Journal of Chemical Biology, vol. 11, no. 1, Jan. 2010, pp. 59–62. Epmc, doi:10.1002/cbic.200900597. Full Text

Crider, Sarah E., et al. “Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1..” Metallomics : Integrated Biometal Science, vol. 2, no. 1, Jan. 2010, pp. 74–83. Epmc, doi:10.1039/b916899k. Full Text Open Access Copy

Haas, Kathryn L., and Katherine J. Franz. “Application of metal coordination chemistry to explore and manipulate cell biology..” Chemical Reviews, vol. 109, no. 10, Oct. 2009, pp. 4921–60. Epmc, doi:10.1021/cr900134a. Full Text

Palmer, Amy E., and Katherine J. Franz. “Introduction to "cellular metal homeostasis and trafficking"..” Chemical Reviews, vol. 109, no. 10, Oct. 2009, pp. 4533–35. Epmc, doi:10.1021/cr900293t. Full Text

Charkoudian, Louise K., et al. “Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide..” Journal of Inorganic Biochemistry, vol. 102, no. 12, Dec. 2008, pp. 2130–35. Epmc, doi:10.1016/j.jinorgbio.2008.08.001. Full Text

Ciesienski, Katie L., et al. “A photolabile ligand for light-activated release of caged copper..” Journal of the American Chemical Society, vol. 130, no. 37, Sept. 2008, pp. 12246–47. Epmc, doi:10.1021/ja8047442. Full Text

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