Faculty Profiles

Katherine J. Franz
Professor in the Department of Chemistry
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Rubino, Jeffrey T., et al. “A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments.Metallomics : Integrated Biometal Science, vol. 3, no. 1, Jan. 2011, pp. 61–73. Epmc, doi:10.1039/c0mt00044b. Full Text

Ciesienski, Katie L., et al. “Development of next-generation photolabile copper cages with improved copper binding properties.Dalton Transactions (Cambridge, England : 2003), vol. 39, no. 40, Oct. 2010, pp. 9538–46. Epmc, doi:10.1039/c0dt00770f. Full Text Open Access Copy

Rubino, Jeffrey T., et al. “Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I).Journal of Biological Inorganic Chemistry : Jbic : A Publication of the Society of Biological Inorganic Chemistry, vol. 15, no. 7, Sept. 2010, pp. 1033–49. Epmc, doi:10.1007/s00775-010-0663-9. Full Text

Ciesienski, Katie L., et al. “Toward the detection of cellular copper(II) by a light-activated fluorescence increase.Inorganic Chemistry, vol. 49, no. 15, Aug. 2010, pp. 6808–10. Epmc, doi:10.1021/ic1004165. Full Text Open Access Copy

Ciesienski, K. L., et al. “A photo-caged platinum(II) complex that increases cytotoxicity upon light activation.” European Journal of Inorganic Chemistry, no. 15, May 2010, pp. 2224–28. Scopus, doi:10.1002/ejic.201000098. Full Text

Folk, Drew S., and Katherine J. Franz. “A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation.Journal of the American Chemical Society, vol. 132, no. 14, Apr. 2010, pp. 4994–95. Epmc, doi:10.1021/ja100943r. Full Text Open Access Copy

Franz, Katherine J., and Chuan He. “The highways and byways of bioinorganic chemistry.Current Opinion in Chemical Biology, vol. 14, no. 2, Apr. 2010, pp. 208–10. Epmc, doi:10.1016/j.cbpa.2010.02.011. Full Text

Perez, Lissette R., and Katherine J. Franz. “Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease.Dalton Transactions (Cambridge, England : 2003), vol. 39, no. 9, Mar. 2010, pp. 2177–87. Epmc, doi:10.1039/b919237a. Full Text Open Access Copy

Tangen, Espen, et al. “Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand.Inorganic Chemistry, vol. 49, no. 6, Mar. 2010, pp. 2701–05. Epmc, doi:10.1021/ic901860x. Full Text

Hyman, Lynne M., et al. “Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress.Dalton Transactions (Cambridge, England : 2003), no. 2, Jan. 2010, pp. 568–76. Epmc, doi:10.1039/b914568k. Full Text