Faculty Profiles

Katherine J. Franz
Chair of the Department of Chemistry
2103 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1541



Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Crumbliss, Alvin L., et al. “Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA.Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine, vol. 28, no. 3, June 2015, p. 431. Epmc, doi:10.1007/s10534-015-9854-8. Full Text

Alies, Bruno, et al. “A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity.Chemical Science, vol. 6, no. 6, June 2015, pp. 3606–10. Epmc, doi:10.1039/c5sc00602c. Full Text

Helsel, Marian E., and Katherine J. Franz. “Pharmacological activity of metal binding agents that alter copper bioavailability.Dalton Transactions (Cambridge, England : 2003), vol. 44, no. 19, May 2015, pp. 8760–70. Epmc, doi:10.1039/c5dt00634a. Full Text

Bureš, Jan, et al. “LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH).Journal of Pharmaceutical and Biomedical Analysis, vol. 105, Feb. 2015, pp. 55–63. Epmc, doi:10.1016/j.jpba.2014.11.044. Full Text

Safi, Rachid, et al. “Copper signaling axis as a target for prostate cancer therapeutics.Cancer Res, vol. 74, no. 20, Oct. 2014, pp. 5819–31. Pubmed, doi:10.1158/0008-5472.CAN-13-3527. Full Text Open Access Copy

Franks, Andrew T., and Katherine J. Franz. “A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting.Chemical Communications (Cambridge, England), vol. 50, no. 77, Oct. 2014, pp. 11317–20. Epmc, doi:10.1039/c4cc05076b. Full Text

Jansová, Hana, et al. “Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury.Free Radical Biology & Medicine, vol. 74, Sept. 2014, pp. 210–21. Epmc, doi:10.1016/j.freeradbiomed.2014.06.019. Full Text

Festa, Richard A., et al. “Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection.Chem Biol, vol. 21, no. 8, Aug. 2014, pp. 977–87. Pubmed, doi:10.1016/j.chembiol.2014.06.009. Full Text

Festa, R. A., et al. “Innate immune cell activation of a copper-dependent anti-cryptococcal agent.” Mycoses, vol. 57, WILEY-BLACKWELL, May 2014, pp. 56–57.

Franks, Andrew T., et al. “Characterization of a photoswitching chelator with light-modulated geometric, electronic, and metal-binding properties.Inorganic Chemistry, vol. 53, no. 3, Feb. 2014, pp. 1397–405. Epmc, doi:10.1021/ic402221x. Full Text


Liu, L. L., and K. J. Franz. “Characterization of metal binding sites in a synthetic phosphorylated alpha-synuclein peptide fragment.Abstracts of Papers of the American Chemical Society, vol. 229, AMER CHEMICAL SOC, 2005, pp. U1080–81.

Franz, Katherine J., et al. “Development of lanthanide-binding peptides as natively expressed protein probes.” Journal of Inorganic Biochemistry, vol. 96, no. 1, Elsevier BV, 2003, pp. 131–131. Crossref, doi:10.1016/s0162-0134(03)80614-1. Full Text