Faculty Profiles

Jiyong Hong
Professor of Chemistry
3220 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1545
(919) 660-1605



Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Chung, B. C., et al. “Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis.” Science, vol. 341, no. 6149, 2013, pp. 1012–16. Scival, doi:10.1126/science.1240985. Full Text

Kaoud, Tamer S., et al. “Manipulating JNK signaling with (--)-zuonin A.Acs Chemical Biology, vol. 7, no. 11, Nov. 2012, pp. 1873–83. Epmc, doi:10.1021/cb300261e. Full Text

Kaoud, Tamer S., et al. “From in Silico Discovery to intra-Cellular Activity: Targeting JNK-Protein Interactions with Small Molecules.Acs Medicinal Chemistry Letters, vol. 3, no. 9, Aug. 2012, pp. 721–25. Epmc, doi:10.1021/ml300129b. Full Text

Lee, Kiyoun, et al. “N-Heterocyclic carbene catalyzed oxidative macrolactonization: total synthesis of (+)-dactylolide.Angewandte Chemie (International Ed. in English), vol. 51, no. 23, June 2012, pp. 5735–38. Epmc, doi:10.1002/anie.201201653. Full Text

Hong, Jiyong, and Hendrik Luesch. “Largazole: from discovery to broad-spectrum therapy.Natural Product Reports, vol. 29, no. 4, Apr. 2012, pp. 449–56. Epmc, doi:10.1039/c2np00066k. Full Text

Lee, K., et al. “Stereoselective synthesis of tetrahydropyrans through tandem and organocatalytic oxa-Michael reactions: Synthesis of the tetrahydropyran cores of ent-(+)-sorangicin A.” European Journal of Organic Chemistry, no. 5, Feb. 2012, pp. 1025–32. Scopus, doi:10.1002/ejoc.201101549. Full Text

Lee, Won-Gil, et al. “Immunosuppressive effects of subglutinol derivatives.Chemmedchem, vol. 7, no. 2, Feb. 2012, pp. 218–22. Epmc, doi:10.1002/cmdc.201100409. Full Text

Park, Heekwang, et al. “A formal synthesis of SCH 351448.Organic Letters, vol. 13, no. 14, July 2011, pp. 3742–45. Epmc, doi:10.1021/ol201426c. Full Text

Hong, Jiyong. “Role of natural product diversity in chemical biology.Current Opinion in Chemical Biology, vol. 15, no. 3, June 2011, pp. 350–54. Epmc, doi:10.1016/j.cbpa.2011.03.004. Full Text