Faculty Profiles

Jiyong Hong
Professor of Chemistry
Office: 
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1545
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Kim, Hyoungsu, et al. “Stereoselective synthesis and osteogenic activity of subglutinols A and B..” Journal of the American Chemical Society, vol. 131, no. 9, Mar. 2009, pp. 3192–94. Epmc, doi:10.1021/ja8101192. Full Text

Lee, Jongkook, et al. “A small molecule inhibitor of alpha4 integrin-dependent cell migration..” Bioorganic & Medicinal Chemistry, vol. 17, no. 3, Feb. 2009, pp. 977–80. Epmc, doi:10.1016/j.bmc.2008.02.067. Full Text

Kim, Hyoungsu, et al. “Nucleophilic addition of organozinc reagents to 2-sulfonyl cyclic ethers: stereoselective synthesis of manassantins A and B..” Org Lett, vol. 11, no. 1, Jan. 2009, pp. 89–92. Pubmed, doi:10.1021/ol8024617. Full Text

Kim, Hyoungsu, et al. “Stereoselective synthesis of 2,6-cis-tetrahydropyrans through a tandem allylic oxidation/oxa-Michael reaction promoted by the gem-disubstituent effect: synthesis of (+)-neopeltolide macrolactone..” Angewandte Chemie (International Ed. in English), vol. 48, no. 41, Jan. 2009, pp. 7577–81. Epmc, doi:10.1002/anie.200903690. Full Text

Ying, Yongcheng, et al. “Synthesis and activity of largazole analogues with linker and macrocycle modification..” Organic Letters, vol. 10, no. 18, Sept. 2008, pp. 4021–24. Epmc, doi:10.1021/ol801532s. Full Text

Ying, Yongcheng, et al. “Total synthesis and molecular target of largazole, a histone deacetylase inhibitor..” Journal of the American Chemical Society, vol. 130, no. 26, July 2008, pp. 8455–59. Epmc, doi:10.1021/ja8013727. Full Text

Lee, Hyunjoo, et al. “A general strategy for construction of both 2,6-cis- and 2,6-trans-disubstituted tetrahydropyrans: substrate-controlled asymmetric total synthesis of (+)-scanlonenyne..” Angewandte Chemie (International Ed. in English), vol. 47, no. 22, Jan. 2008, pp. 4200–03. Epmc, doi:10.1002/anie.200705663. Full Text

Ying, Y., and J. Hong. “Synthesis of brasilibactin A and confirmation of absolute configuration of β-hydroxy acid fragment.” Tetrahedron Letters, vol. 48, no. 46, Nov. 2007, pp. 8104–07. Scopus, doi:10.1016/j.tetlet.2007.09.112. Full Text

Lee, Jongkook, et al. “A small-molecule antagonist of the hedgehog signaling pathway..” Chembiochem : A European Journal of Chemical Biology, vol. 8, no. 16, Nov. 2007, pp. 1916–19. Epmc, doi:10.1002/cbic.200700403. Full Text

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