Faculty Profiles

Jiyong Hong
Professor of Chemistry
3220 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1545
(919) 660-1605



Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University (South Korea) 1995

B.S., Seoul National University (South Korea) 1993

Research Areas:
Synthesis, Biological, Organic

Lee, Minhee, et al. “Structure-Activity Relationship of Sulfonyl Piperazine LpxH Inhibitors Analyzed by an LpxE-Coupled Malachite Green Assay.Acs Infect Dis, vol. 5, no. 4, Apr. 2019, pp. 641–51. Pubmed, doi:10.1021/acsinfecdis.8b00364. Full Text

Eubanks, Amber L., et al. “In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.Chemmedchem, vol. 13, no. 23, Dec. 2018, pp. 2479–83. Epmc, doi:10.1002/cmdc.201800625. Full Text

Kwon, Do-Yeon, et al. “Synthetic efforts towards the stereoselective synthesis of NF00659B1.Bioorganic & Medicinal Chemistry Letters, vol. 28, no. 16, Sept. 2018, pp. 2746–50. Epmc, doi:10.1016/j.bmcl.2018.02.038. Full Text

Siska, Peter J., et al. “Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma.Jci Insight, vol. 2, no. 12, June 2017. Pubmed, doi:10.1172/jci.insight.93411. Full Text

Kim, Bumki, et al. “Synthesis and biological evaluation of largazole zinc-binding group analogs.Bioorganic & Medicinal Chemistry, vol. 25, no. 12, June 2017, pp. 3077–86. Epmc, doi:10.1016/j.bmc.2017.03.071. Full Text

Lanier, Megan L., et al. “Formal Synthesis of (+)-Laurencin by Gold(I)-Catalyzed Intramolecular Dehydrative Alkoxylation.Chemistry (Weinheim an Der Bergstrasse, Germany), vol. 23, no. 30, May 2017, pp. 7180–84. Epmc, doi:10.1002/chem.201700499. Full Text

Siska, Peter J., et al. “Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes.J Immunol Methods, vol. 438, Nov. 2016, pp. 51–58. Pubmed, doi:10.1016/j.jim.2016.08.013. Full Text

Lee, Kiyoun, et al. “Advances in the synthesis of glycosidic macrolides: clavosolides A-D and cyanolide A.Natural Product Reports, vol. 33, no. 12, Nov. 2016, pp. 1393–424. Epmc, doi:10.1039/c6np00073h. Full Text

Geer Wallace, M. Ariel, et al. “Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements.J Proteome Res, vol. 15, no. 8, Aug. 2016, pp. 2688–96. Pubmed, doi:10.1021/acs.jproteome.6b00237. Full Text

Chung, Ben C., et al. “Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.Nature, vol. 533, no. 7604, May 2016, pp. 557–60. Pubmed, doi:10.1038/nature17636. Full Text