Faculty Profiles

Jiyong Hong
Professor of Chemistry
Office: 
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1545
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University (South Korea) 1995

B.S., Seoul National University (South Korea) 1993

Research Areas:
Synthesis, Biological, Organic

Lim, Wonchung, et al. “Subglutinol A, an immunosuppressive α-pyrone diterpenoid from Fusarium subglutinans, acts as an estrogen receptor antagonist.Biochemical and Biophysical Research Communications, vol. 461, no. 3, June 2015, pp. 507–12. Epmc, doi:10.1016/j.bbrc.2015.04.053. Full Text

Kim, Bumki, and Jiyong Hong. “An overview of naturally occurring histone deacetylase inhibitors.Current Topics in Medicinal Chemistry, vol. 14, no. 24, Jan. 2015, pp. 2759–82. Epmc, doi:10.2174/1568026615666141208105614. Full Text

Hong, Jiyong. “Natural product synthesis at the interface of chemistry and biology.Chemistry (Weinheim an Der Bergstrasse, Germany), vol. 20, no. 33, Aug. 2014, pp. 10204–12. Epmc, doi:10.1002/chem.201402804. Full Text

Kim, Bumki, et al. “Evaluation of class I HDAC isoform selectivity of largazole analogues.Bioorganic & Medicinal Chemistry Letters, vol. 24, no. 16, Aug. 2014, pp. 3728–31. Epmc, doi:10.1016/j.bmcl.2014.07.006. Full Text

Salvador, Lilibeth A., et al. “Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties.Acs Medicinal Chemistry Letters, vol. 5, no. 8, Aug. 2014, pp. 905–10. Epmc, doi:10.1021/ml500170r. Full Text

Johnson, Zachary Lee, et al. “Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.Elife, vol. 3, July 2014, p. e03604. Pubmed, doi:10.7554/eLife.03604. Full Text

Johnson, Zachary Lee, et al. “Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.” Elife, vol. 3, July 2014. Wos-lite, doi:10.7554/eLife.03604. Full Text

Lin, Regina, et al. “Biological evaluation of subglutinol a as a novel immunosuppressive agent for inflammation intervention.Acs Med Chem Lett, vol. 5, no. 5, May 2014, pp. 485–90. Pubmed, doi:10.1021/ml4004809. Full Text

Lanier, Megan L., et al. “Synthesis of α,α'-trans-oxepanes through an organocatalytic oxa-conjugate addition reaction.Organic Letters, vol. 16, no. 9, May 2014, pp. 2406–09. Epmc, doi:10.1021/ol500773w. Full Text

Yu, Mingming, et al. “Largazole pharmacokinetics in rats by LC-MS/MS.Marine Drugs, vol. 12, no. 3, Mar. 2014, pp. 1623–40. Epmc, doi:10.3390/md12031623. Full Text

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