Faculty Profiles

Jiyong Hong
Professor of Chemistry
Office: 
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1545
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Kim, Bumki, et al. “Evaluation of class I HDAC isoform selectivity of largazole analogues.Bioorganic & Medicinal Chemistry Letters, vol. 24, no. 16, Aug. 2014, pp. 3728–31. Epmc, doi:10.1016/j.bmcl.2014.07.006. Full Text

Salvador, Lilibeth A., et al. “Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties.Acs Medicinal Chemistry Letters, vol. 5, no. 8, Aug. 2014, pp. 905–10. Epmc, doi:10.1021/ml500170r. Full Text

Johnson, Zachary Lee, et al. “Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.Elife, vol. 3, July 2014, p. e03604. Pubmed, doi:10.7554/eLife.03604. Full Text

Johnson, Zachary Lee, et al. “Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.” Elife, vol. 3, July 2014. Wos-lite, doi:10.7554/eLife.03604. Full Text

Lin, Regina, et al. “Biological evaluation of subglutinol a as a novel immunosuppressive agent for inflammation intervention.Acs Med Chem Lett, vol. 5, no. 5, May 2014, pp. 485–90. Pubmed, doi:10.1021/ml4004809. Full Text

Lanier, Megan L., et al. “Synthesis of α,α'-trans-oxepanes through an organocatalytic oxa-conjugate addition reaction.Organic Letters, vol. 16, no. 9, May 2014, pp. 2406–09. Epmc, doi:10.1021/ol500773w. Full Text

Yu, Mingming, et al. “Largazole pharmacokinetics in rats by LC-MS/MS.Marine Drugs, vol. 12, no. 3, Mar. 2014, pp. 1623–40. Epmc, doi:10.3390/md12031623. Full Text

Strickland, Erin C., et al. “False-positive rate determination of protein target discovery using a covalent modification- and mass spectrometry-based proteomics platform.Journal of the American Society for Mass Spectrometry, vol. 25, no. 1, Jan. 2014, pp. 132–40. Epmc, doi:10.1007/s13361-013-0754-2. Full Text

Chung, Ben C., et al. “Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis.Science, vol. 341, no. 6149, Aug. 2013, pp. 1012–16. Pubmed, doi:10.1126/science.1236501. Full Text

Law, M. E., et al. “Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms.Oncogene, vol. 32, no. 10, Mar. 2013, pp. 1316–29. Epmc, doi:10.1038/onc.2012.138. Full Text

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