Faculty Profiles

Jiyong Hong
Professor of Chemistry
3220 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1545
(919) 660-1605



Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Harrington, James M., et al. “Characterization of Fe(III) sequestration by an analog of the cytotoxic siderophore brasilibactin A: implications for the iron transport mechanism in mycobacteria..” Metallomics : Integrated Biometal Science, vol. 3, no. 5, May 2011, pp. 464–71. Epmc, doi:10.1039/c0mt00109k. Full Text

Lee, Su-Ui, et al. “In Vitro and In Vivo Osteogenic Activity of Largazole..” Acs Medicinal Chemistry Letters, vol. 2, no. 3, Mar. 2011, pp. 248–51. Epmc, doi:10.1021/ml1002794. Full Text

Ying, Yongcheng, et al. “Stereoselective synthesis of 2,6-cis- and 2,6-trans-piperidines through organocatalytic aza-Michael reactions: a facile synthesis of (+)-myrtine and (-)-epimyrtine..” Organic Letters, vol. 13, no. 4, Feb. 2011, pp. 796–99. Epmc, doi:10.1021/ol103064f. Full Text

Liu, Yanxia, et al. “Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor..” The Journal of Pharmacology and Experimental Therapeutics, vol. 335, no. 2, Nov. 2010, pp. 351–61. Epmc, doi:10.1124/jpet.110.172387. Full Text

Kim, Hyoungsu, et al. “Total synthesis, assignment of the absolute stereochemistry, and structure-activity relationship studies of subglutinols A and B..” Chemistry, an Asian Journal, vol. 5, no. 8, Aug. 2010, pp. 1902–10. Epmc, doi:10.1002/asia.201000147. Full Text

Kim, Hyoungsu, and Jiyong Hong. “Total synthesis of cyanolide A and confirmation of its absolute configuration..” Organic Letters, vol. 12, no. 12, June 2010, pp. 2880–83. Epmc, doi:10.1021/ol101022z. Full Text Open Access Copy

Yuan, Langtian, et al. “Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse..” Mol Biosyst, vol. 5, no. 9, Sept. 2009, pp. 927–30. Pubmed, doi:10.1039/b903036k. Full Text

Kasper, Amanda C., et al. “Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations..” Bioorg Med Chem Lett, vol. 19, no. 14, July 2009, pp. 3783–86. Pubmed, doi:10.1016/j.bmcl.2009.04.071. Full Text

Kasper, Amanda C., et al. “The end game of chemical genetics: target identification..” Future Medicinal Chemistry, vol. 1, no. 4, July 2009, pp. 727–36. Epmc, doi:10.4155/fmc.09.52. Full Text