Faculty Profiles

Jiyong Hong
Professor of Chemistry
3220 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1545
(919) 660-1605



Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Kim, Bumki, et al. “Synthesis and biological evaluation of largazole zinc-binding group analogs.Bioorganic & Medicinal Chemistry, vol. 25, no. 12, June 2017, pp. 3077–86. Epmc, doi:10.1016/j.bmc.2017.03.071. Full Text

Lanier, Megan L., et al. “Formal Synthesis of (+)-Laurencin by Gold(I)-Catalyzed Intramolecular Dehydrative Alkoxylation.Chemistry (Weinheim an Der Bergstrasse, Germany), vol. 23, no. 30, May 2017, pp. 7180–84. Epmc, doi:10.1002/chem.201700499. Full Text

Siska, Peter J., et al. “Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes.J Immunol Methods, vol. 438, Nov. 2016, pp. 51–58. Pubmed, doi:10.1016/j.jim.2016.08.013. Full Text

Lee, Kiyoun, et al. “Advances in the synthesis of glycosidic macrolides: clavosolides A-D and cyanolide A.Natural Product Reports, vol. 33, no. 12, Nov. 2016, pp. 1393–424. Epmc, doi:10.1039/c6np00073h. Full Text

Geer Wallace, M. Ariel, et al. “Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements.J Proteome Res, vol. 15, no. 8, Aug. 2016, pp. 2688–96. Pubmed, doi:10.1021/acs.jproteome.6b00237. Full Text

Chung, Ben C., et al. “Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.Nature, vol. 533, no. 7604, May 2016, pp. 557–60. Pubmed, doi:10.1038/nature17636. Full Text

Kwon, Do-Yeon, et al. “Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition.J Med Chem, vol. 58, no. 19, Oct. 2015, pp. 7659–71. Pubmed, doi:10.1021/acs.jmedchem.5b01220. Full Text

Baker, Joseph B., et al. “Total Synthesis of Clavosolide A via Tandem Allylic Oxidation/Oxa-Conjugate Addition Reaction.Tetrahedron Letters, vol. 56, no. 23, June 2015, pp. 3120–22. Epmc, doi:10.1016/j.tetlet.2014.11.135. Full Text

Lim, Wonchung, et al. “Subglutinol A, an immunosuppressive α-pyrone diterpenoid from Fusarium subglutinans, acts as an estrogen receptor antagonist.Biochemical and Biophysical Research Communications, vol. 461, no. 3, June 2015, pp. 507–12. Epmc, doi:10.1016/j.bbrc.2015.04.053. Full Text

Kim, Bumki, and Jiyong Hong. “An overview of naturally occurring histone deacetylase inhibitors.Current Topics in Medicinal Chemistry, vol. 14, no. 24, Jan. 2015, pp. 2759–82. Epmc, doi:10.2174/1568026615666141208105614. Full Text