Faculty Profiles

Eric John Toone
Professor Emeritus of Chemistry
3236 French Science Center, Durham, NC 27708
(919) 660-1506
(919) 660-1591



Ph.D., University of Toronto (Canada) 1988

M.S., University of Toronto (Canada) 1985

B.S., University of Guelph (Canada) 1983

Research Areas:
Synthesis, Physical, Organic

DiTusa, CA, McCall, KA, Christensen, T, Mahapatro, M, Fierke, CA, and Toone, EJ. "Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants." Biochemistry 40.18 (May 8, 2001): 5345-5351.

DiTusa, CA, Christensen, T, McCall, KA, Fierke, CA, and Toone, EJ. "Thermodynamics of metal ion binding. 1. Metal ion binding by wild-type carbonic anhydrase." Biochemistry 40.18 (May 2001): 5338-5344. Full Text

Wymer, N, Buchanan, LV, Henderson, D, Mehta, N, Botting, CH, Pocivavsek, L, Fierke, CA, Toone, EJ, and Naismith, JH. "Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli." Structure 9.1 (January 10, 2001): 1-9.

Ditusa, CA, Fierke, CA, and Toone, EJ. "Thermodynamics of Metal Ion Bonding. II. Metal Ion Binding by Mutated Carbonic Anhydrases." Biochemistry 40.18 (2001): 5345-5351. (Academic Article)

Lundquist, JJ, Debenham, SD, and Toone, EJ. "Multivalency effects in protein--carbohydrate interaction: the binding of the Shiga-like toxin 1 binding subunit to multivalent C-linked glycopeptides." The Journal of Organic Chemistry 65.24 (December 2000): 8245-8250. Full Text

Trzaska, SM, Toone, EJ, and Crumbliss, AL. "Microcalorimetric determination of thermodynamic parameters for ionophore-siderophore host-guest complex formation." Inorg Chem 39.6 (March 20, 2000): 1071-1075.

Debenham, SD, and Toone, EJ. "Regioselective reduction of 4,6-O-benzylidenes using triethylsilane and BF3.Et2O." Tetrahedron Asymmetry 11.2 (February 11, 2000): 385-387. Full Text

Wymer, N, and Toone, EJ. "Enzyme-catalyzed synthesis of carbohydrates." Curr Opin Chem Biol 4.1 (February 2000): 110-119. (Review)

Corbell, JB, Lundquist, JJ, and Toone, EJ. "A comparison of biological and calorimetric analyses of multivalent glycodendrimer ligands for concanavalin A." Tetrahedron Asymmetry 11.1 (January 28, 2000): 95-111. Full Text

Debenham, S, and Toone, EJ. "A Facile Method for the Reductive Deprotection of Carbohydrate Benzylidene Protecting Groups." Tetrahedron Asymm. (2000): 385-387. (Academic Article)