Faculty Profiles

Eric John Toone
Professor Emeritus of Chemistry
3236 French Science Center, Durham, NC 27708
(919) 660-1506
(919) 660-1591



Ph.D., University of Toronto (Canada) 1988

M.S., University of Toronto (Canada) 1985

B.S., University of Guelph (Canada) 1983

Research Areas:
Synthesis, Physical, Organic

Wymer, N, Buchanan, LV, Henderson, D, Mehta, N, Botting, CH, Pocivavsek, L, Fierke, CA, Toone, EJ, and Naismith, JH. "Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli." Structure 9.1 (January 10, 2001): 1-9.

Ditusa, CA, Fierke, CA, and Toone, EJ. "Thermodynamics of Metal Ion Bonding. II. Metal Ion Binding by Mutated Carbonic Anhydrases." Biochemistry 40.18 (2001): 5345-5351. (Academic Article)

Lundquist, JJ, Debenham, SD, and Toone, EJ. "Multivalency effects in protein--carbohydrate interaction: the binding of the Shiga-like toxin 1 binding subunit to multivalent C-linked glycopeptides." The Journal of Organic Chemistry 65.24 (December 2000): 8245-8250. Full Text

Trzaska, SM, Toone, EJ, and Crumbliss, AL. "Microcalorimetric determination of thermodynamic parameters for ionophore-siderophore host-guest complex formation." Inorg Chem 39.6 (March 20, 2000): 1071-1075.

Wymer, N, and Toone, EJ. "Enzyme-catalyzed synthesis of carbohydrates." Curr Opin Chem Biol 4.1 (February 2000): 110-119. (Review)

Debenham, S, and Toone, EJ. "A Facile Method for the Reductive Deprotection of Carbohydrate Benzylidene Protecting Groups." Tetrahedron Asymm. (2000): 385-387. (Academic Article)

Corbell, JB, Lundquist, JJ, and Toone, EJ. "Biological and Calorimetric Analysis of Multivalent Glycodendrimers Ligands for Concanavalin A." Tetrahedron Asymm. 11 (2000): 95-111. (Academic Article)

Lundquist, JJ, Debenham, SD, and Toone, EJ. "Calorimetric and Biological Evaluation of Shigalike Toxin1 Binding to Multivalent C-Linked Glycopeptides." J. Org. Chem. 65 (2000): 8245-8250. (Academic Article)

Wymer, N, and Toone, EJ. "Enzymatic Carbohydrate Synthesis." Current Opinion in Chemical Biology 4 (2000): 110-119. (Academic Article)

Bartberger, MD, Houk, KN, Powell, S, Mannion, J, Lo, KYK, Stamler, JS, and Toone, EJ. "Nuclear Magnetic Resonance and Visible Spectroscopy of S-Nitrosothiols. Conformational Distribution Dictates Spectroscopic Behavior." J. Am. Chem. Soc. 122 (2000): 5889-5890. (Academic Article)