Faculty Profiles

Eric John Toone
Professor Emeritus of Chemistry
Office: 
3236 French Science Center, Durham, NC 27708
Phone: 
(919) 660-1506
Fax: 
(919) 660-1591

Overview

Education:

Ph.D., University of Toronto (Canada) 1988

M.S., University of Toronto (Canada) 1985

B.S., University of Guelph (Canada) 1983

Research Areas:
Synthesis, Physical, Organic

Walters, MJ, Srikannathasan, V, McEwan, AR, Naismith, JH, Fierke, CA, and Toone, EJ. "Characterization and crystal structure of Escherichia coli KDPGal aldolase." Bioorganic & Medicinal Chemistry 16.2 (January 2008): 710-720. Full Text

Sidebotham, D, McKee, A, Gillham, M, and Levy, JH. "Preface." Cardiothoracic Critical Care (December 1, 2007). Full Text

Shestopalov, AA, Clark, RL, and Toone, EJ. "Inkless microcontact printing on self-assembled monolayers of fmoc-protected aminothiols." J Am Chem Soc 129.45 (November 14, 2007): 13818-13819. Full Text

Cheriyan, M, Toone, EJ, and Fierke, CA. "Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates." Protein Science : a Publication of the Protein Society 16.11 (November 2007): 2368-2377. Full Text

Snyder, PW, Johannes, MS, Vogen, BN, Clark, RL, and Toone, EJ. "Biocatalytic microcontact printing." J Org Chem 72.19 (September 14, 2007): 7459-7461. Full Text

Matsuoka, K, Goshu, Y, Takezawa, Y, Mori, T, Sakamoto, JI, Yamada, A, Onaga, T, Koyama, T, Hatano, K, Snyder, PW, Toone, EJ, and Terunuma, D. "Practical synthesis of fully protected globotriaose and its glycopolymers." Carbohydrate Polymers 69.2 (June 1, 2007): 326-335. Full Text

Snyder, PW, Lee, G, Marszalek, PE, Clark, RL, and Toone, EJ. "A stochastic, cantilever approach to the evaluation of solution phase thermodynamic quantities." Proc Natl Acad Sci U S A 104.8 (February 20, 2007): 2579-2584. Full Text

Cheryian, M, Toone, EJ, and Fierke, CA. "Substrate specificity of the electrophilic binding site of KDPG aldolase is altered by mutagenesis (Submitted)." Bioorg. Med. Chem. (2007). (Academic Article)

Walters, MJ, and Toone, EJ. "Pyruvate aldolases in chiral carbon-carbon bond formation." Nature Protocols 2.7 (January 2007): 1825-1830. Full Text

Perry, JL, Goldsmith, MR, Williams, TR, Radack, KP, Christensen, T, Gorham, J, Pasquinelli, MA, Toone, EJ, Beratan, DN, and Simon, JD. "Binding of warfarin influences the acid-base equilibrium of H242 in sudlow site I of human serum albumin." Photochem Photobiol 82.5 (September 2006): 1365-1369. Full Text

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