Faculty Profiles

Emily R. Derbyshire
Assistant Professor of Chemistry
Office: 
3218 French Science Center, Durham, NC 27708
Phone: 
(919) 660-1511

Overview

Education:

NIH Postdoctoral Fellow, Biological Chemistry & Molecular Pharmacology, Harvard Medical School 2009 - 2014

Ph.D., University of California at Berkeley 2008

B.S., Trinity College 2002

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Ganley, Jack G., et al. “Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes.Chembiochem : A European Journal of Chemical Biology, vol. 19, no. 15, Aug. 2018, pp. 1590–94. Epmc, doi:10.1002/cbic.201800124. Full Text

Posfai, Dora, et al. “Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.Plos Pathog, vol. 14, no. 5, May 2018, p. e1007057. Pubmed, doi:10.1371/journal.ppat.1007057. Full Text Open Access Copy

Posfai, Dora, et al. “Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.” Plos Pathogens, vol. 14, no. 5, PUBLIC LIBRARY SCIENCE, May 2018. Wos, doi:10.1371/journal.ppat.100757. Full Text

Posfai, Dora, et al. “Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity.Antimicrob Agents Chemother, vol. 62, no. 4, Apr. 2018. Pubmed, doi:10.1128/AAC.01799-17. Full Text

Ganley, Jack G., et al. “Exploring the Untapped Biosynthetic Potential of Apicomplexan Parasites.Biochemistry, vol. 57, no. 4, Jan. 2018, pp. 365–75. Epmc, doi:10.1021/acs.biochem.7b00877. Full Text

Totzke, Juliane, et al. “Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.Cell Chem Biol, vol. 24, no. 8, Aug. 2017, pp. 1029-1039.e7. Pubmed, doi:10.1016/j.chembiol.2017.07.011. Full Text

Kato, Nobutaka, et al. “Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.Nature, vol. 538, no. 7625, Oct. 2016, pp. 344–49. Epmc, doi:10.1038/nature19804. Full Text

Raphemot, Rene, et al. “Current therapies and future possibilities for drug development against liver-stage malaria.The Journal of Clinical Investigation, vol. 126, no. 6, June 2016, pp. 2013–20. Epmc, doi:10.1172/jci82981. Full Text

Raphemot, Rene, et al. “Discovery of Dual-Stage Malaria Inhibitors with New Targets.Antimicrobial Agents and Chemotherapy, vol. 60, no. 3, Dec. 2015, pp. 1430–37. Epmc, doi:10.1128/aac.02110-15. Full Text

Herman, Jonathan D., et al. “The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.Science Translational Medicine, vol. 7, no. 288, May 2015, p. 288ra77. Epmc, doi:10.1126/scitranslmed.aaa3575. Full Text

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