Faculty Profiles

Emily R. Derbyshire
Assistant Professor of Chemistry
3218 French Science Center, Durham, NC 27708
(919) 660-1511



NIH Postdoctoral Fellow, Biological Chemistry & Molecular Pharmacology, Harvard Medical School 2009 - 2014

Ph.D., University of California at Berkeley 2008

B.S., Trinity College 2002

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Raphemot, Rene, et al. “Discovery of Druggable Host Factors Critical to Plasmodium Liver-Stage Infection..” Cell Chemical Biology, vol. 26, no. 9, Sept. 2019, pp. 1253-1262.e5. Epmc, doi:10.1016/j.chembiol.2019.05.011. Full Text

Szamosvári, Dávid, et al. “Close the ring to break the cycle: tandem quinolone-alkyne-cyclisation gives access to tricyclic pyrrolo[1,2-a]quinolin-5-ones with potent anti-protozoal activity..” Chemical Communications (Cambridge, England), vol. 55, no. 49, June 2019, pp. 7009–12. Epmc, doi:10.1039/c9cc01689a. Full Text

Lee, Hyunji, et al. “Synthesis and Analysis of Natural-Product-Like Macrocycles by Tandem Oxidation/Oxa-Conjugate Addition Reactions..” Chemistry (Weinheim an Der Bergstrasse, Germany), vol. 25, no. 26, May 2019, pp. 6500–04. Epmc, doi:10.1002/chem.201900620. Full Text

Raphemot, Rene, et al. “Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites..” Cell Chem Biol, vol. 26, no. 3, Mar. 2019, pp. 411-419.e7. Pubmed, doi:10.1016/j.chembiol.2018.11.003. Full Text

Eubanks, Amber L., et al. “In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors..” Chemmedchem, vol. 13, no. 23, Dec. 2018, pp. 2479–83. Epmc, doi:10.1002/cmdc.201800625. Full Text

Ganley, Jack G., et al. “Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes..” Chembiochem : A European Journal of Chemical Biology, vol. 19, no. 15, Aug. 2018, pp. 1590–94. Epmc, doi:10.1002/cbic.201800124. Full Text

Posfai, Dora, et al. “Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection..” Plos Pathog, vol. 14, no. 5, May 2018. Pubmed, doi:10.1371/journal.ppat.1007057. Full Text Open Access Copy

Posfai, Dora, et al. “Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.” Plos Pathogens, vol. 14, no. 5, PUBLIC LIBRARY SCIENCE, May 2018. Wos, doi:10.1371/journal.ppat.100757. Full Text

Posfai, Dora, et al. “Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity..” Antimicrob Agents Chemother, vol. 62, no. 4, Apr. 2018. Pubmed, doi:10.1128/AAC.01799-17. Full Text

Ganley, Jack G., et al. “Exploring the Untapped Biosynthetic Potential of Apicomplexan Parasites..” Biochemistry, vol. 57, no. 4, Jan. 2018, pp. 365–75. Epmc, doi:10.1021/acs.biochem.7b00877. Full Text