Faculty Profiles

Dewey G. McCafferty
Professor of Chemistry
B120 LSRC, Box 90346, 450 Research Drive, Dept. Chemistry, Durham, NC 27708-0346
(919) 660-1516
(919) 660-1605



Ph.D., University of North Carolina at Chapel Hill 1995

B.S., North Carolina State University 1990

Research Areas:
Synthesis, Biomolecular Structure and Function, Biological, Organic

Gaweska, H, Kielec, J, and McCafferty, D. "A suppression strategy for antibiotic discovery." Chemistry and Biology 11.10 (2004): 1330-1332. Full Text

Frankel, BA, and McCafferty, DG. "Profiling natural product biosynthesis." Chemistry and Biology 11.3 (2004): 290-291. Full Text

Kruger, RG, Otvos, B, Frankel, BA, Bentley, M, Dostal, P, and McCafferty, DG. "Analysis of the Substrate Specificity of the Staphylococcus aureus Sortase Transpeptidase SrtA." Biochemistry 43.6 (2004): 1541-1551. Full Text

Loyola, A, He, S, Oh, S, McCafferty, DG, and Reinberg, D. "Techniques Used to Study Transcription on Chromatin Templates." Methods in Enzymology 377 (2004): 474-499. Full Text

He, S, Bauman, D, Davis, JS, Loyola, A, Nishioka, K, Gronlund, JL, Reinberg, D, Meng, F, Kelleher, N, and McCafferty, DG. "Facile synthesis of site-specifically acetylated and methylated histone proteins: reagents for evaluation of the histone code hypothesis." Proceedings of the National Academy of Sciences of the United States of America 100.21 (October 6, 2003): 12033-12038. Full Text

Kapustin, GV, Fejér, G, Gronlund, JL, McCafferty, DG, Seto, E, and Etzkorn, FA. "Phosphorus-based SAHA analogues as histone deacetylase inhibitors." Organic Letters 5.17 (August 2003): 3053-3056. Full Text

Huang, C-Y, He, S, DeGrado, WF, McCafferty, DG, and Gai, F. "Light-Induced Helix Formation." Journal of the American Chemical Society 124.43 (October 2002): 12674-12675. Full Text

Cudic, P, Kranz, JK, Behenna, DC, Kruger, RG, Tadesse, H, Wand, AJ, Veklich, YI, Weisel, JW, and McCafferty, DG. "Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: Minimal structural requirements for intermolecular complexation and fibril formation." Proceedings of the National Academy of Sciences of the United States of America 99.11 (2002): 7384-7389. Full Text

McCafferty, DG, Cudic, P, Frankel, BA, Barkallah, S, Kruger, RG, and Li, W. "Chemistry and biology of the ramoplanin family of peptide antibiotics." Biopolymers 66.4 (January 2002): 261-284. (Review) Full Text